Inventors:
Harinderpal Chhabra - New Brunswick NJ 08901
Shyamal K. Sarkar - Blauvelt NY 10913-1150
International Classification:
A61K 922
US Classification:
424474, 424468, 424470, 424472, 424475, 514770, 5147723, 514777, 514778, 514779, 514780, 514781, 514782
Abstract:
A pharmaceutical composition for controlled onset and sustained release of an active ingredient, said composition comprising: (i) a core comprising: (a) an active ingredient; (b) a hydrophilic carrier; (c) a hydrodynamic diffusion enhancer; and optionally (d) conventional pharmaceutically acceptable excipients selected from the group consisting of binders, fillers and lubricants and combinations thereof; and (ii) a functional coating membrane surrounding said core.