SHEILA MARGARET NOLAN
Medical Practice in Pleasantville, NY
License number
Pennsylvania MD428132
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Pleasantville, NY 10570
Pennsylvania
Pennsylvania
Personal information
See more information about SHEILA MARGARET NOLAN at radaris.comName
Address
Phone
108 Sagamore Rd APT 6G, Tuckahoe, NY 10707
525 Riverleigh Ave UNIT 107A, Riverhead, NY 11901
60 Dalston Rd, Rochester, NY 14616
436 Lower Main St APT 1, Hudson Falls, NY 12839
6 Cheryl Ln N, Farmingdale, NY 11735
Professional information
Attenuated Human Parainfluenza Virus, Methods And Uses Thereof
US Patent:
2013005, Feb 28, 2013
Filed:
Jan 10, 2006
Appl. No.:
13/501447
Inventors:
Mario H. Skiadopoulos - Potomac MD, US
Peter L. Collins - Silver Spring MD, US
Sheila Nolan - Pleasantville NY, US
Peter L. Collins - Silver Spring MD, US
Sheila Nolan - Pleasantville NY, US
Assignee:
THE GOVERNMENT OF THE US, REPRESENTED BY THE SECRETARY , DEPT. OF HEALTH AND HUMAN SERVICES - Rockville MD
International Classification:
C12N 7/04, C12N 7/01
US Classification:
435236, 4352351
Abstract:
The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the recombinant paramyxovirus has a separate variant polynucleotide encoding a P protein and a separate monocistronic polynucleotide encoding a V protein. In some embodiments, recombinant paramyxovirus have at least one temperature sensitive mutation and one non-temperature sensitive mutation. Also provided are compositions and methods for using the recombinant paramyxoviruses as described herein.