Inventors:
Shanthi Srinivasan - Atlanta GA, US
Assignee:
US GOVERNMENT REPRESENTED BY THE US DEPARTMENT OF VETERANS AFFAIRS - Washington DC
EMORY UNIVERSITY - Atlanta GA
International Classification:
A61K 38/18
Abstract:
The disclosure relates to therapeutic methods for regulating weight gain, metabolic syndrome, and insulin resistance. In certain embodiments, the disclosure relates to methods of treating or preventing obesity, metabolic syndrome, or insulin resistance by administering an effective amount of a pharmaceutical composition comprising one or more GDNF receptor agonists to a subject in need thereof.