DR. SERGE PRZEDBORSKI, M.D., PHD
Neurology at 168 St, New York, NY
License number
New York 195280-1
Category
Neurology
Type
Neurology
Address
Address
710 W 168Th St, New York, NY 10032
Phone
(212) 305-1992
Personal information
See more information about SERGE PRZEDBORSKI at radaris.comName
Address
Phone
101 W 67Th St Ph 3A, New York, NY 10023
New York, NY
101 67Th St, New York, NY 10023
101 67Th St, New York, NY 10023
101 W 67Th St, New York, NY 10023
Organization information
See more information about SERGE PRZEDBORSKI at bizstanding.comSerge Przedborski MD,PHD
650 W 168 St, New York, NY 10032
Industry:
Neurologist
Phone:
(212) 305-1992 (Phone)
Serge Eric Przedborski
Serge Przedborski MD
630 W 168 St, New York, NY 10032
Categories:
Physicians & Surgeons
Phone:
(212) 305-2500 (Phone)
Professional information
Serge Eric Przedborski, New York NY
Specialties:
Neurology
Work:
Neurological Institute
710 W 168Th St, New York, NY 10032 Columbia University
650 W 168Th St, New York, NY 10032
710 W 168Th St, New York, NY 10032 Columbia University
650 W 168Th St, New York, NY 10032
Education:
Universite Libre De Bruxelles (1983)
Serge Eric Przedborski, New York NY
Specialties:
Neurologist
Address:
710 W 168Th St, New York, NY 10032
Dr. Serge Przedborski, New York NY - MD (Doctor of Medicine)
Specialties:
Neurology
Address:
Clmb Unvrsty Nrscnc Rsrch Lbrty
630 W 168Th St SUITE 420, New York 10032
(212) 305-1992 (Phone)
630 W 168Th St SUITE 420, New York 10032
(212) 305-1992 (Phone)
Languages:
English
Stem Cell-Based Culture System For Drug Development
US Patent:
2010026, Oct 21, 2010
Filed:
Apr 10, 2008
Appl. No.:
12/450830
Inventors:
Serge Przedborski - New York NY, US
Hynek Wichterle - New York NY, US
Makiko Nagai - Okayama, JP
Thomas M. Jessell - Bronx NY, US
Hynek Wichterle - New York NY, US
Makiko Nagai - Okayama, JP
Thomas M. Jessell - Bronx NY, US
International Classification:
C12Q 1/02, C12N 5/079, C12N 5/0793
US Classification:
435 29, 435347, 435325
Abstract:
The present invention relates to culture systems comprising differentiated stem cells, that may be used for identifying agents useful in treating degenerative nervous system disorders and are suitable for high-throughput screening applications. It is based, at least in part, on the discovery that co-cultures of (i) astrocytes expressing a mutated SODI gene and (ii) stem-cell derived motor neurons manifested cell death via a Bax-dependent mechanism, and modeled motor neuron death in amyotrophic lateral sclerosis.