SEOK HO LEE
Pharmacy in Cranford, NJ
License number
Pennsylvania RP037109L
Category
Pharmacy
Type
Pharmacist
Address
Address
2
Cranford, NJ 07016
Pennsylvania
Pennsylvania
Personal information
See more information about SEOK HO LEE at radaris.comName
Address
Phone
53 Chadwick Cir, Eagleville, PA 19403
67 Diamond Dr, Newtown, PA 18940
711 Shaler Blvd, Ridgefield, NJ 07657
671A Bruce St, Ridgefield, NJ 07657
169 Carmita Ave, Rutherford, NJ 07070
Professional information
Indole Diterpene Alkaloid Compounds
US Patent:
5541208, Jul 30, 1996
Filed:
Jan 24, 1994
Appl. No.:
8/186197
Inventors:
Maria L. Garcia - Edison NJ
Robert A. Giacobbe - Lavellette NJ
Otto D. Hensens - Red Bank NJ
Seok H. Lee - Cranford NJ
Owen B. McManus - North Plainfield NJ
Deborah L. Zink - Manalapan NJ
Robert A. Giacobbe - Lavellette NJ
Otto D. Hensens - Red Bank NJ
Seok H. Lee - Cranford NJ
Owen B. McManus - North Plainfield NJ
Deborah L. Zink - Manalapan NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3141, A61K 31395, C07D49822
US Classification:
514379
Abstract:
The present invention relates to compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof which are useful as potassium channel antagonists, particularly Maxi-K channel antagonists, and thus useful in treating Alzheimer's Disease and other cognitive disorders. This invention is also related to a method of making the compound of formula (I).
Biologically Active Compounds
US Patent:
5399587, Mar 21, 1995
Filed:
Dec 13, 1993
Appl. No.:
8/166499
Inventors:
Maria L. Garcia - Edison NJ
Robert A. Giacobbe - Lavellette NJ
Otto D. Hensens - Red Bank NJ
Gregory J. Kaczorowski - Edison NJ
Seok H. Lee - Cranford NJ
Owen B. McManus - North Plainfield NJ
Deborah L. Zink - Manalapan NJ
Robert A. Giacobbe - Lavellette NJ
Otto D. Hensens - Red Bank NJ
Gregory J. Kaczorowski - Edison NJ
Seok H. Lee - Cranford NJ
Owen B. McManus - North Plainfield NJ
Deborah L. Zink - Manalapan NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A01K 3135
US Classification:
514451
Abstract:
The present invention relates to novel potassium channel agonists which are useful in activating the calcium activated Maxi-K potassium channel in mammalian neuronal and smooth muscle tissue. The claimed compounds are of the general formula: ##STR1## In addition, a novel microbiological process for producing the claimed compounds is described.