SEAN ERIC MCGUIRE, MD
Radiology at Holcombe Blvd, Houston, TX
License number
Texas M2398
Category
Radiology
Type
Radiation Oncology
Address
Address
1515 Holcombe Blvd, Houston, TX 77030
Phone
(713) 792-6161
Personal information
See more information about SEAN ERIC MCGUIRE at radaris.comName
Address
Phone
4712 Holly St, Bellaire, TX 77401
443 Marshall Rd, Southlake, TX 76092
4333 Beall Blvd, Abilene, TX 79606
4202 Maple Cross Dr, Pasadena, TX 77505
411 Buckingham Rd APT 1416, Richardson, TX 75081
Professional information
Sean Eric McGuire, Houston TX
Specialties:
Oncologist
Address:
1515 Holcombe Blvd, Houston, TX 77030
Education:
Doctor of Medicine
Board certifications:
American Board of Radiology Certification in Radiation Oncology (Radiology)
Dr. Sean E Mcguire, Houston TX - MD (Doctor of Medicine)
Specialties:
Radiation Oncology
Address:
1515 Holcombe Blvd SUITE 1202, Houston 77030
(713) 792-5905 (Phone), (713) 563-6876 (Fax)
Houston Office
1515 Holcombe Blvd SUITE 10, Houston 77030
(877) 632-6789 (Phone)
(713) 792-5905 (Phone), (713) 563-6876 (Fax)
Houston Office
1515 Holcombe Blvd SUITE 10, Houston 77030
(877) 632-6789 (Phone)
Certifications:
Radiation Oncology, 2010
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1515 Holcombe Blvd SUITE 1202, Houston 77030
Houston Office
1515 Holcombe Blvd SUITE 10, Houston 77030
The University of Texas M.D. Anderson Cancer Center
1515 Holcombe Blvd, Houston 77030
Houston Office
1515 Holcombe Blvd SUITE 10, Houston 77030
The University of Texas M.D. Anderson Cancer Center
1515 Holcombe Blvd, Houston 77030
Education:
Medical School
Baylor Coll Of Med
Graduated: 1999
Baylor Coll Of Med
Graduated: 1999
Genotyping For Src-1 Predicts For Bone Loss
US Patent:
2009026, Oct 29, 2009
Filed:
Nov 20, 2008
Appl. No.:
12/275195
Inventors:
Steffi Oesterreich - Missouri City TX, US
Alexandra Richter - Houston TX, US
Adrian Lee - Missouri City TX, US
C. Kent Osborne - Houston TX, US
Sean E. Mcguire - Houston TX, US
Ryan Hartmaier - Houston TX, US
Alexandra Richter - Houston TX, US
Adrian Lee - Missouri City TX, US
C. Kent Osborne - Houston TX, US
Sean E. Mcguire - Houston TX, US
Ryan Hartmaier - Houston TX, US
Assignee:
BAYLOR COLLEGE OF MEDICINE - Houston TX
International Classification:
C12Q 1/68, C12Q 1/48
US Classification:
435 6, 435 15
Abstract:
Osteoporosis is a common skeletal disease characterized by loss of bone mineral density (BMD) and increased risk of fracture. Osteoporosis most commonly occurs in postmenopausal women due to estrogen deficiency. We identified 3 genetic variants in steroid receptor coactivator 1 (SRC-1) that are significantly associated with a decrease in BMD in women. We characterized a functional variant in exon 18 of SRC-1 that is associated with increased loss of bone mineral density in women who received tamoxifen for treatment or prevention of breast cancer. In vitro experiments show that this variant decreases estrogen receptor alpha response (ER-alpha) to hormone, suggesting an attenuated response to endogenous and exogenous hormones in the bone of these women, and therefore a need for additional bone protective measures.