Inventors:
Ted Gross - Seattle WA, US
Steve Bain - Shoreline WA, US
Sean Nork - Seattle WA, US
Assignee:
UNIVERSITY OF WASHINGTON TRHOUGH IT'S CENTER FOR COMMERCIALIZATION - SEATTLE WA
International Classification:
A61K 38/16, A61K 31/445, A61P 25/00, A61P 19/08, A61P 17/02, A61K 31/167, A61K 31/4745
US Classification:
514 167, 514626, 514330, 514279
Abstract:
Described are methods of inhibiting heterotopic ossification (HO) in a subject in need thereof. The methods involve administering an effective amount of a proprioception inhibitor to the subject, whereby HO is inhibited or prevented. The present invention also relates to a method of treating a subject with bone trauma. This involves administering a proprioception inhibitor to the subject under conditions effective to treat the bone trauma, where the proprioception inhibitor prevents or inhibits HO.