Inventors:
Bernard O. Palsson - San Diego CA, US
Natalie Duarte - Scottsdale AZ, US
Scott Becker - San Diego CA, US
Neema Jamshidi - La Jolla CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G06F 19/00, G06F 7/00
Abstract:
The present invention provides Recon 1, a manually assembled, functionally validated, bottom-up reconstruction of human metabolism. Recon 1's 1496 genes, 2004 proteins, 2766 metabolites, and 3311 biochemical and transport reactions were extracted from more than 50 years of legacy biochemical knowledge and Build 35 of the human genome sequence.