SCOTT KENDALL DESSAIN
Medical Practice in Penn Wynne, PA

License number
Pennsylvania MD420102
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096

Personal information

See more information about SCOTT KENDALL DESSAIN at radaris.com
Name
Address
Phone
Scott Dessain, age 61
1370 Indian Creek Dr, Wynnewood, PA 19096
Scott K Dessain, age 61
1370 Indian Creek Dr, Wynnewood, PA 19096
(610) 896-9979

Professional information

Scott Dessain Photo 1

Fusion Partner Cells And Uses Thereof

US Patent:
2003022, Dec 4, 2003
Filed:
Dec 18, 2002
Appl. No.:
10/324114
Inventors:
Scott Dessain - Wynnewood PA, US
Robert Weinberg - Cambridge MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12P021/04, C12N005/06, C07K016/18
US Classification:
435/070210, 435/326000, 530/387100, 435/451000
Abstract:
The present invention provides in one aspect novel fusion partner cells that ectopically express one or more genes that alter the phenotype of a hybrid cell made from a fusion of the fusion partner cell and a fusion cell, hybrid cell lines produced using the fusion partner cells. The invention in another aspect provides antibodies produced by certain hybrid cell lines, and compositions containing one or a combination of such antibodies or antigen-binding fragments thereof. The invention also provides in another aspect methods of using the antibodies or antigen-binding fragments thereof for diagnosis and treatment of diseases characterized by the antigens specifically bound by the antibodies.


Scott K Dessain Photo 2

Dr. Scott K Dessain, Wynnewood PA - MD (Doctor of Medicine)

Specialties:
Oncology, Medical Oncology
Address:
100 E Lancaster Ave SUITE 227, Wynnewood 19096
(484) 476-6516 (Phone)
Certifications:
Internal Medicine, 1997, Medical Oncology, 2001
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
100 E Lancaster Ave SUITE 227, Wynnewood 19096
Lankenau Medical Center
100 East Lancaster Ave, Wynnewood 19096
Education:
Medical School
Yale University School Of Medicine
Graduated: 1994
Brigham&Womens Hospital
Graduated: 1996
Dana Farber Cancer Center
Graduated: 2000
Whitehead Institute Biomedical Rsrch
Graduated: 2002


Scott Dessain Photo 3

Fusion Partner Cell Line For Preparation Of Hybrid Cells Expressing Human Antibodies

US Patent:
8557575, Oct 15, 2013
Filed:
Jan 28, 2009
Appl. No.:
12/864896
Inventors:
Scott K. Dessain - Wynnewood PA, US
Sharad P. Adekar - Secane PA, US
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C12N 5/00
US Classification:
435346
Abstract:
This invention relates to a novel fusion partner cell line that ectopically expresses IL-6 and TERT termed B5-6T, and to methods for making the B5-6T fusion partner cell line. The B5-6T fusion partner cell line can be fused with B-lymphocytes to generate hybridomas that secrete human monoclonal antibodies.


Scott Dessain Photo 4

Use Of Immunoglobulin Heavy And Light Chains Or Fragments Thereof To Bind To Aggregated Amyloidogenic Proteins

US Patent:
2011000, Jan 6, 2011
Filed:
Jun 25, 2010
Appl. No.:
12/803384
Inventors:
Brian O'Nuallain - Dublin, IE
Scott Dessain - Wynnewood PA, US
Sharad Adekar - Secane PA, US
International Classification:
A61K 39/395, C07K 16/18, A61P 25/28
US Classification:
4241721, 5303891
Abstract:
Subunits of antibodies, such as a light chain or a heavy chain, selectively bind to amyloid fibrils and oligomers.


Scott Dessain Photo 5

Method Of Making Hybrid Cells That Express Useful Antibodies

US Patent:
2011000, Jan 6, 2011
Filed:
Jan 28, 2009
Appl. No.:
12/864889
Inventors:
Scott K. Dessain - Wynnewood PA, US
Sharad P. Adekar - Secane PA, US
Assignee:
THOMAS JEFFERSON UNIVERSITY - Philadelphia PA
International Classification:
A61K 39/40, C12N 5/12, C07K 16/00, C12P 21/08, C07H 21/00, C40B 50/06, C40B 40/10, A61P 31/04, A61P 25/00
US Classification:
4241501, 435326, 5303881, 435 7021, 5303871, 5303873, 536 2353, 506 26, 506 18, 4241671
Abstract:
This invention relates to a novel hybridoma strategy that uses CD27+ B cells cultured in vitro to induce IgM to IgG class switch prior to fusion with a fusion partner. Hybridomas resulting from the fusion between CD27+ B cells and a fusion partner cell line and antibodies secreted from the hybridomas are included in the invention.


Scott Dessain Photo 6

Monoclonal Antibodies That Neutralize Botulinum Neurotoxin

US Patent:
2010022, Sep 2, 2010
Filed:
Jun 19, 2006
Appl. No.:
11/455507
Inventors:
Scott K. Dessain - Wynnewood PA, US
Lance L. Simpson - Moorestown NJ, US
Sharad P. Adekar - Secane PA, US
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C07K 16/12, C07K 14/00, C07H 21/04, A61K 39/395, A61P 43/00, G01N 33/53
US Classification:
5303873, 5303871, 530350, 536 231, 4241671, 4241351, 436501
Abstract:
This invention provides antibodies that specifically bind to botulinum neurotoxin type A (BoNT/A) and/or botulinum neurotoxin type B (BoNT/B) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism. Also included in the invention are diagnostic and therapeutic assays directed to botulinum neurotoxins.