Inventors:
Scott H. Korn - Richboro PA
Gerard P. McNally - Strafford PA
Joseph R. Luber - Quakertown PA
Tom S. Ells - Fort Washington PA
Assignee:
Merck & Co., Inc. - Rahway NY
McNeil-PPC, Inc. - Skillman NJ
International Classification:
A61K 920, A61K 948
Abstract:
A method for preventing heartburn episodes in a patient at risk to development of heartburn, comprising administering to the patient, following the heartburn inducing event but prior to development of heartburn, a composition comprising a pharmaceutically effective amount of an H. sub. 2 antagonist and an amount of antacid having between about 15 mEq and 46 mEq acid neutralizing capacity.