Allergy & Immunology, Internal Medicine, Pulmonary Disease, Critical Care Medicine, Pediatrics, Critical Care Medicine
Work:
Governors Village 101 Manning Dr, Chapel Hill, NC 27514
Education:
University of Michigan Medical School (1990)
Scott H Donaldson, Chapel Hill NC
Specialties:
Pulmonologist
Address:
101 Manning Dr, Chapel Hill, NC 27514
Education:
University of Michigan, Medical School - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Sub-certificate in Pulmonary Disease (Internal Medicine)
Dr. Scott H Donaldson, Chapel Hill NC - MD (Doctor of Medicine)
Specialties:
Critical Care Medicine, Pulmonology
Address:
101 Manning Dr SUITE 7001J, Chapel Hill 27514 (919) 966-4191 (Phone), (919) 843-5515 (Fax)
Certifications:
Critical Care Medicine, 1999, Internal Medicine, 1993, Pulmonary Disease, 1996
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
101 Manning Dr SUITE 7001J, Chapel Hill 27514 University of North Carolina Hospital 101 Manning Dr, Chapel Hill 27514
Education:
Medical School University of Mi Med Sch Graduated: 1990 Dartmouth-Hitchcock Mc U Nc
Regulation Of Sodium Channels By Plunc Proteins
US Patent:
2012011, May 10, 2012
Filed:
May 28, 2010
Appl. No.:
13/321617
Inventors:
Robert Tarran - Chapel Hill NC, US Monroe Jack Stutts - Chapel Hill NC, US Scott Donaldson - Chapel Hill NC, US
International Classification:
A61K 38/14, C07H 21/04, C12N 5/02, C07K 14/435
US Classification:
514 209, 530395, 536 235, 435375
Abstract:
The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.