Inventors:
Scott A. Small - New York NY, US
International Classification:
A61K 49/00, A61K 31/551, A61K 31/519, A61K 31/445, A61K 31/137
US Classification:
424 9361, 514220, 514317, 514649, 51425941
Abstract:
This invention provides a method for treating a mammalian subject afflicted with a disorder associated with reduced neurogenesis in the subject's hippocampal dentate gyrus which comprises administering to the subject a therapeutically effective amount of a compound which increases cerebral blood volume in the subject's hippocampal dentate gyrus by a percentage greater than that by which it increases the cerebral blood volume in the subject's hippocampal CA1 region, thereby treating the subject.