Inventors:
Scott Tomlins - Ann Arbor MI, US
Daniel Rhodes - Ann Arbor MI, US
Arul Chinnaiyan - Ann Arbor MI, US
Rohit Mehra - Ann Arbor MI, US
Mark A. Rubin - New York NY, US
Xiao-Wei Sun - New York NY, US
Sven Perner - Ellwaugen, DE
Charles Lee - Marlborough MA, US
Francesca Demichelis - New York NY, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
The Brigham and Women's Hospital - Boston MA
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/04
US Classification:
435 612, 435 912, 435810, 536 221, 536 243
Abstract:
Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.