SATORU TODO
Medical Practice in Pittsburgh, PA
License number
Pennsylvania LT000045L
Category
Medicine
Type
Institutional License
Address
Address
Pittsburgh, PA 15261
Professional information
Method For Treating Pyoderma And Sezary's Syndrome Using Fk 506 And Related Compounds
US Patent:
5348966, Sep 20, 1994
Filed:
Nov 22, 1993
Appl. No.:
8/155533
Inventors:
Thomas E. Starzl - Pittsburgh PA
Satoru Todo - Pittsburgh PA
Satoru Todo - Pittsburgh PA
Assignee:
Fujisawa Pharmaceutical Co., Ltd. - Osaka
International Classification:
A61K 31445, A61K 3133, A61K 3140
US Classification:
514326
Abstract:
Administration of FK506 or related macrolide compounds is effective for the treatment of pyoderma and Sezary's syndrome.
Method For Treating Hepatic Diseases And Regenerating Liver Tissue Using Fk 506 And Related Compounds
US Patent:
5196437, Mar 23, 1993
Filed:
Dec 18, 1990
Appl. No.:
7/629028
Inventors:
Thomas E. Starzl - Pittsburgh PA
Satoru Todo - Pittsburgh PA
Antonio Francavilla - Pittsburgh PA
Satoru Todo - Pittsburgh PA
Antonio Francavilla - Pittsburgh PA
Assignee:
Fujisawa Pharmaceutical Company, Ltd. - Osaka
International Classification:
A61K 3144, A61K 3140
US Classification:
514294
Abstract:
Macrolide compounds having the structure shown below ##STR1## wherein R. sup. 1 is hydroxy or protected hydroxy, R. sup. 2 is hydrogen, hydroxy or protected hydroxy, R. sup. 3 is methyl, ethyl, propyl or allyl, R. sup. 4 is hydroxy, methoxy or oxo, n is 1 or 2 and the symbol of a line and a dotted is a single bond or a double bond, provided that R. sup. 2 is not protected hydroxy where R. sup. 4 is hydroxy or oxo are used to treat hepatic disease and regenerate liver tissue by facilitating hypertrophy and hyperplasia of hepatocytes.