Inventors:
Shelly Glase - Ann Arbor MI
Juan C. Jaen - Plymouth MI
Sarah J. Smith - Boulder CO
Lawrence D. Wise - Ann Arbor MI
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 3147, C07D21538, C07D21724, C07D40306
Abstract:
Substituted tetrahydropyridines and hydroxypiperidines and derivatives thereof are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.