Inventors:
Istvan Boldogh - Galveston TX, US
Sanjiv Sur - Houston TX, US
International Classification:
A61K 36/18, A61K 31/375, A61K 31/353, A61K 31/198, A61K 31/355
US Classification:
424725000, 514456000, 514458000, 514474000, 514562000
Abstract:
Disclosed are methods for treating or preventing allergic inflammation in a subject and methods for treating or preventing one or more symptoms of allergic inflammation in a subject. The methods include administering to the subject a compound which inhibits reactive oxygen species. Also disclosed are methods for reducing a non-animal-derived allergen's ability to initiate an allergenic process and for reducing prooxidant activity of a non-animal-derived allergen. The methods include contacting the non-animal-derived allergen with an agent which inhibits reactive oxygen species. Methods for screening a compound for its usefulness as an agent for reducing a non-animal-derived allergen's ability to initiate an allergenic process and/or for its usefulness as a therapeutic agent for treating or preventing allergic inflammation and/or the symptoms associated therewith are also disclosed.