Inventors:
Chris D. Geddes - Bel-Air MD, US
Sanjiv Amin - Silver Spring MD, US
Assignee:
UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE - Baltimore MD
International Classification:
G01N 33/00, G01N 27/64
Abstract:
The present invention relates to metallic-surface detection systems for determining target substances including free bilirubin in neonatal serum in the presence of a predominantly high background of bilirubin bound Human Serum Albumin (HSA) or sensing and isolating target nucleotide sequences wherein a fluorescence signal is enhanced by close proximity of the target substances near metallic surfaces.