SANGWOOK TIM YOON, MD/PHD
Medical Practice at Executive Park South, Atlanta, GA
License number
Georgia 49126
Category
Medical Practice
Type
Orthopaedic Surgery of the Spine
Address
Address
59 Executive Park South NE STE 3000, Atlanta, GA 30329
Phone
(404) 778-7155
Personal information
See more information about SANGWOOK TIM YOON at radaris.comName
Address
Phone
2647 Tyler Manor Ct, Decatur, GA 30033
2431 Valhalla Dr, Atlanta, GA 30345
Professional information
Sangwook Yoon, Atlanta GA
Specialties:
Orthopaedic Surgery, Orthopaedic Surgery of the Spine, Surgery
Work:
Emory Orthopaedics & Spine Center
59 Executive Park South SUITE 3000, Atlanta, GA 30329 Atlanta Va Medical Center
1670 Clairmont Rd, Decatur, GA 30033
59 Executive Park South SUITE 3000, Atlanta, GA 30329 Atlanta Va Medical Center
1670 Clairmont Rd, Decatur, GA 30033
Education:
Yale University (1994)
Methods Of Expressing Lim Mineralization Protein In Non-Osseous Cells
US Patent:
2003018, Sep 25, 2003
Filed:
Nov 13, 2002
Appl. No.:
10/292951
Inventors:
William McKay - Memphis TN, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
International Classification:
A61K048/00, A61F002/44, C07H021/04, C12N005/08
US Classification:
424/093210, 514/044000, 514/012000, 530/350000, 536/023500, 623/017110, 435/366000
Abstract:
Methods of expressing LIM mineralization protein in non-osseous mammalian cells, such as stem cells or intervertebral disc cells (e.g., cells of the annulus fibrosus, or cells of the nucleus pulposus) are described. The methods involve transfecting the cells with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. Transfection may be accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. Expression of the LIM mineralization protein can stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycyan and/or collagen. Methods for treating disc disease associated with trauma or disc degeneration are also described.
Methods Of Inducing The Expression Of Bone Morphogenetic Proteins (Bmps) And Transforming Growth Factor-Beta Proteins (Tgf-Betas) In Cells
US Patent:
2003022, Dec 4, 2003
Filed:
Mar 7, 2003
Appl. No.:
10/382844
Inventors:
William McKay - Memphis TN, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
International Classification:
A61K048/00, C12N005/08, C12N015/861, C12N015/867
US Classification:
514/044000, 424/093200, 435/456000, 435/366000
Abstract:
A method of inducing the expression of one or more bone morphogenetic proteins and/or transforming growth factor- proteins in a cell is described. The method includes transfecting a cell with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. The one or more bone morphogenetic proteins can be BMP-2, BMP-4, BMP-6, BMP-7 or combinations thereof. The transforming growth factor- protein can be transforming growth factor-1 protein (TGF-1). Transfection may be accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. The method can be used to induce bone formation in osseous cells or to stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycyan and/or collagen (e.g., intervertebral disc cells).
Methods Of Inducing Or Increasing The Expression Of Proteoglycans Such As Aggrecan In Cells
US Patent:
2007013, Jun 14, 2007
Filed:
Nov 21, 2006
Appl. No.:
11/602805
Inventors:
William McKay - Memphis TN, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
International Classification:
A61K 48/00
US Classification:
424093210, 514044000
Abstract:
Methods of inducing the expression of a proteoglycan such as aggrecan in a cell are described. A method is described which includes transfecting a cell with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. The LIM mineralization protein can be rLMP, hLMP-1, hLMP-1s, or hLMP-3. Transfection maybe accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. The method can be used to induce proteoglycan synthesis in osseous cells or to stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycan and/or collagen (e.g., intervertebral disc cells including cells of the nucleus pulposus and annulus fibrosus).
Intracellular Delivery Of Osteoinductive Proteins And Peptides
US Patent:
2004019, Oct 7, 2004
Filed:
Mar 23, 2004
Appl. No.:
10/806915
Inventors:
Frances Titus - Atlanta GA, US
Jeffrey Marx - Germantown TN, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
Susan Drapeau - Cordova TN, US
Jeffrey Marx - Germantown TN, US
Scott Boden - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
Susan Drapeau - Cordova TN, US
International Classification:
C12P021/02, C07K014/475, C07H021/04
US Classification:
435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:
The invention provides fusion polypeptides comprising protein transduction domains and osteoinductive polypeptides, as well as methods of using such polypeptides to induce osteogenesis and to promote proteoglycan synthesis. The invention also provides osteoinductive peptides which have demonstrated the ability to induce bone formation in vivo.
Chondrogenic Compositions And Methods Of Use
US Patent:
2007000, Jan 11, 2007
Filed:
May 30, 2006
Appl. No.:
11/443387
Inventors:
Susan Drapeau - Cordova TN, US
Sangwook Yoon - Atlanta GA, US
Sangwook Yoon - Atlanta GA, US
International Classification:
A61K 35/14, C12N 5/08
US Classification:
424093700, 435366000
Abstract:
The invention provides a method of treatment joint and disk disease comprising administering to the subject in need thereof a novel composition comprising a substantially purified plurality of cells enhanced with at least one bioactive factor capable of causing at least a portion of the plurality of cells to express an increased amount of at least one chondrogenic marker.