Inventors:
Kirk P. Conrad - Gainesville FL, US
Arundhathi Jeyabalan - Pittsburgh PA, US
Sandra Anne Founds - Wexford PA, US
William Allen Hogge - Pittsburgh PA, US
Assignee:
University of Pittsburgh-Of the Commonwealth System of Higher Education - Pittsburgh PA
University of Florida Research Foundation, Inc. - Gainesville FL
International Classification:
C12Q 1/68, G01N 33/53
Abstract:
Gene expression patterns contemporaneous with early placental development in the first trimester of preeclamptic versus unaffected pregnancies have been obtained. Observation of differences in these gene expression patterns has allowed the identification of biomarkers that are useful in predicting and monitoring preeclampsia. These biomarkers are also useful in screening potential therapeutics for efficacy in the prevention or treatment of preeclampsia.