Inventors:
Sami A. Hashim - Dobbs Ferry NY, US
Joanna Jusis - Lincoln Park NJ, US
Jenifer Heydinger Galante - Oakland NJ, US
Joseph C. Rongione - Middletown NJ, US
International Classification:
A61K 31/22, A61K 31/23, A61P 25/28, A61P 25/08, A61P 25/16
Abstract:
Provided are alternative sources of ketone bodies for reducing or eliminating symptoms of Parkinson's disease, amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's disease), Alzheimer's disease, Huntington's disease, epilepsy and other diseases or disorders characterized by impaired glucose metabolism. The alternative sources of ketone bodies include mono-, di- and triglyceride esters of acetoacetate and mixtures thereof, and/or mono-, di- and triglyceride esters of 3-hydroxybutyrate and mixtures thereof. These glyceride esters can be administered orally as a dietary supplement or in a nutritional composition.