Inventors:
Scott Panzer - Sunnyvale CA, US
Stephen Lincoln - Potomac MD, US
Christina Altus - Campbell CA, US
Gerard Dufour - Castro Valley CA, US
Jennifer Jackson - Santa Cruz CA, US
Anissa Jones - San Jose CA, US
Tam Dam - San Jose CA, US
Tommy Liu - Daly City CA, US
Bernard Harris - Sunnyvale CA, US
Vincent Flores - Union City CA, US
Abel Daffo - San Jose CA, US
Rakesh Marwaha - Burnaby, BR
Alice Chen - San Jose CA, US
Simon Chang - Sunnyvale CA, US
Edward Gerstin Jr - San Jose CA, US
Careyna Peralta - Santa Clara CA, US
Marie David - Daly City CA, US
Samantha Lewis - San Leandro CA, US
International Classification:
C12Q001/68, C07H021/04, C12P019/34, C12P021/02, C12N005/06, C07K014/00
US Classification:
435/006000, 536/023200, 435/091200, 435/069100, 435/320100, 435/325000, 530/350000
Abstract:
The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.