Inventors:
Ying Sun - Wakefield RI, US
Frederick J. Vetter - South Kingston RI, US
Rumei Dong - Kingston RI, US
Salvatore A. Chiaramida - Charleston SC, US
Assignee:
Board of Governors for Higher Education, State of Rhode Island and Providence Plantations - Providence RI
International Classification:
A61B 5/05
Abstract:
A computational model which integrates a complex circulatory model and a finite element to determine the dynamics of a left ventricle continuously over consecutive cardiac cycles. The model includes determining a LV pressure (p) using a circulatory model, using a finite element model pas input and determining a LV volume (v), computing a LV elastance according to: e=p/v, driving the circulatory model with the e; and returning to determining a LV pressure and starting the next iteration, wherein the steps continue at a sufficient time resolution for a desired number of entire cardiac cycles. The dynamic Young's modulus functions are assigned to individual finite elements, resulting in a time-varying left ventricular elastance that drives the circulatory model.