DR. SABINE BROUXHON, MD
Osteopathic Medicine in Stonybrook, NY
License number
New York 220288
Category
Osteopathic Medicine
Type
Emergency Medicine
Address
Address
Stony Brook University Medical Ctr Hsc L4 RM 080, Stonybrook, NY 11794
Phone
(631) 444-2478
(631) 444-3919 (Fax)
(631) 444-3919 (Fax)
Organization information
See more information about SABINE BROUXHON at bizstanding.comSabine Brouxhon MD
Hsc Level 4 Room, Stonybrook, NY 11794
Industry:
Emergency Medicine
Phone:
(631) 444-2478 (Phone)
Sabine Monique Brouxhon
Professional information
Dr. Sabine Brouxhon, Stony Brook NY - MD (Doctor of Medicine)
Specialties:
Emergency Medicine
Address:
Rm 80 STE L4, Stony Brook 11794
(631) 444-2478 (Phone), (631) 444-3919 (Fax)
STONY BROOK UNIVERSITY HOSPITAL
Hsc Level STE 4, Stony Brook 11794
(631) 444-2478 (Phone), (631) 444-3919 (Fax)
(631) 444-2478 (Phone), (631) 444-3919 (Fax)
STONY BROOK UNIVERSITY HOSPITAL
Hsc Level STE 4, Stony Brook 11794
(631) 444-2478 (Phone), (631) 444-3919 (Fax)
Certifications:
Emergency Medicine, 2011
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Rm 80 STE L4, Stony Brook 11794
STONY BROOK UNIVERSITY HOSPITAL
Hsc Level STE 4, Stony Brook 11794
Strong Memorial Hospital
601 Elmwood Ave, Rochester 14642
STONY BROOK UNIVERSITY HOSPITAL
Hsc Level STE 4, Stony Brook 11794
Strong Memorial Hospital
601 Elmwood Ave, Rochester 14642
Education:
Medical School
University of Rochester
Graduated: 1997
Strong Mem Hsp University Rochester
University of Rochester
Graduated: 1997
Strong Mem Hsp University Rochester
Compositions Targeting The Soluble Extracellular Domain Of E-Cadherin And Related Methods For Cancer Therapy
US Patent:
2013028, Oct 31, 2013
Filed:
Oct 27, 2011
Appl. No.:
13/882078
Inventors:
Sabine Brouxhon - Stony Brook NY, US
M. Kerry O'Banion - Pittsford NY, US
Stephanos Kyrkanides - Stony Brook NY, US
M. Kerry O'Banion - Pittsford NY, US
Stephanos Kyrkanides - Stony Brook NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 39/395, A61K 39/00, G01N 33/50, C07K 14/47, C07K 16/18, A61K 45/00, G01N 33/574
US Classification:
4241391, 514 44 R, 4241851, 4241781, 435 792, 530395, 5303879, 4353201, 435 71
Abstract:
The present invention is based, in part, on our discovery that targeting epitopes within one or more of the EC2-EC5 subdomains of E-cadherin results in the death of epithelial-derived tumor cells but not in the death of normal, healthy epithelial cells or non-epithelial cells including endothelial cells and fibroblasts. Accordingly, the compositions of the invention include poly-peptides having an amino acid sequence of one or more of the EC2-EC5 subdomains of E-cadherin and biologically active variants thereof; expression vectors and cells for expressing such polypeptides; and agents (e.g., antibodies) that target the EC2-EC5 subdomains. The methods of the invention include methods of identifying and producing polypeptides having an amino acid sequence of one or more of the EC2-EC5 subdomains of E-cadherin or a biologically active variant thereof; methods of generating agents, such as antibodies, that target these polypeptides; and methods of administering such agents or eliciting their production in vivo to treat epithelial cancers or reduce the risk of their occurrence or recurrence.
Compositions And Methods Relating To Detection Of Soluble E-Cadherin In Neurodegenerative Disease
US Patent:
2011016, Jul 7, 2011
Filed:
May 26, 2009
Appl. No.:
12/994324
Inventors:
Sabine M. Brouxhon - Stony Brook NY, US
Ross H. Tallents - Rochester NY, US
M. Kerry O'Banion - Pittsford NY, US
Ross H. Tallents - Rochester NY, US
M. Kerry O'Banion - Pittsford NY, US
International Classification:
G01N 33/53, G01N 33/68
US Classification:
436501, 436 87
Abstract:
Disclosed herein are compositions and methods for diagnosing, detecting, or monitoring neural disease, conditions, or disorders involving detection of soluble E-cadherin.