RUTH JOSEPHINE MUSCHEL
Medical Practice in Philadelphia, PA
License number
Pennsylvania MD039052E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Philadelphia, PA 19103
Professional information
Sensitization Of Cells To Radiation And And Chemotherapy
US Patent:
2002003, Mar 21, 2002
Filed:
Apr 15, 1997
Appl. No.:
08/839248
Inventors:
W. GILLIES MCKENNA - PHILADELPHIA PA, US
RUTH J. MUSCHEL - PHILADELPHIA PA, US
ERIC J. BERNHARD - PHILADELPHIA PA, US
SAID M. SEBTI - TAMPA FL, US
ANDREW D. HAMILTON - PITTSBURGH PA, US
RUTH J. MUSCHEL - PHILADELPHIA PA, US
ERIC J. BERNHARD - PHILADELPHIA PA, US
SAID M. SEBTI - TAMPA FL, US
ANDREW D. HAMILTON - PITTSBURGH PA, US
International Classification:
A61M036/14, A61K051/00, A01N037/18, A61K038/00, C12Q001/00, C12Q001/68, G01N033/53, A61K038/16, A61K031/70, A01N043/04, A61K039/395, A61K031/545, G01N033/52
US Classification:
435/004000, 514/002000, 514/044000, 435/006000, 435/007100, 424/130100, 424/001110
Abstract:
The invention relates to a method of conferring radiation sensitivity on a tumor cell comprising administering to the cell an inhibitor of a protein product which participates in the ras signalling pathway, whereby inhibition of the protein product confers radiation sensitivity on the cell.