Inventors:
Russell S. Taichman - Ann Arbor MI
Stephen G. Emerson - Wayne PA
Assignee:
The Regent of the University of Michigan - Ann Arbor MI
International Classification:
A01N 6302, C12N 500, C12N 506
Abstract:
Processes, compositions and uses of hematopoietic cells are disclosed. Hematopoietic cells are cells which can differentiate into mature blood cells when co-cultured with osteoblasts. Specifically, a process for propagating and maintaining the immature morphology of a hematopoietic cell by co-culturing with osteoblasts is disclosed. The osteoblasts provide cytokines and/or a microenvironment which propagates and maintains the immature morphology of a hematopoietic cell. Hematopoietic cells are useful in the treatment of certain blood related disorders and are useful for treatment of patients in need of hematopoietic cells.