DR. RUBIO REYES PUNZALAN, M.D.
Osteopathic Medicine at Encino Dr, Pasadena, CA

2004026, Dec 30, 2004

Apr 7, 2004

10/819398

Denis Rodgerson - Malibu CA, US
Thomas Hirose - Huntington Beach CA, US
Rubio Punzalan - Pasadena CA, US

A61K045/00, C12Q001/68, G01N001/30, G01N033/48, C12N005/08

424/093700, 435/040500, 435/366000

A system provides individualized “baseline” or internal “control” for an individual by collecting cells from the individual at an earlier time point prior to the onset of disease, which can be used as a standard for normalcy and a benchmark or reference for measuring the progression or development of any process the cells undergo. This allows study of biophysical, biochemical, architectural, morphological, functional, or physiological differences between cells collected from an individual at one time to cells collected from the same individual at a later point in time. The comparison between cells collected at different times allows for the study of relative responses of these cells when treated with a variety of chemicals. With this system disease markers can be determined that can aid in diagnosis and discovery of therapeutics for the disease of interest. As a result, this system may provide a basis for the production of patient-specific, as opposed to disease-specific drugs.