Inventors:
Victor Levenson - Chicago IL, US
Anatoliy Melnikov - Glenview IL, US
Roumen Balabanov - Chicago IL, US
Dusan Stefoski - Chicago IL, US
Assignee:
RUSH UNIVERSITY MEDICAL CENTER - Chicago IL
International Classification:
C12Q 1/68
Abstract:
A DNA methylation-based test for efficiency of treatments is based on a plurality of genes. The test is suitable for monitoring treatment of subjects with neurological diseases, e.g., multiple sclerosis (MS); with cancer, e.g., breast and ovarian cancer, and with other diseases for which methylation of biomarkers differs in the diseased compared to the non-diseased state.