Inventors:
Roslyn Rivkah Isseroff - Sacramento CA, US
Christine E. Pullar - Sacramento CA, US
International Classification:
A61K 31/5377, C07D 417/12, C07C 237/32, A61K 31/166, C07C 215/56, A61K 31/138, C07D 209/88, A61K 31/403, C07D 215/20, A61K 31/4704, C07C 215/64, C07C 311/32, A61K 31/18, C07C 215/60, A61K 31/137, A61K 9/00, A61P 17/02, A61P 27/02
US Classification:
424423, 544134, 5142362, 564165, 514620, 564428, 514652, 548444, 514411, 546158, 514312, 564443, 514650, 564 99, 514605, 514653
Abstract:
Methods for increasing rate of healing of wounds in epithelial tissues by administration of beta-2 adrenergic receptor antagonists to target patients are provided. Methods for decreasing cell growth around implanted devices and methods for decreasing wound contraction by administration of beta-2 adrenergic receptor agonists are also provided. Pharmaceutical compositions and kits including beta-2 adrenergic receptor agonists and antagonists are described, as are devices coated with beta-2 adrenergic receptor agonists.