RONALD BERENSON, M.D.
Medical Laboratory at 41 Ave, Seattle, WA
License number
Washington MD 00022209
Category
Medical Laboratory
Type
Physiological Laboratory
Address
Address
2
2032 41St Ave, Seattle, WA 98112
PO Box 1597, Mercer Island, WA 98040
PO Box 1597, Mercer Island, WA 98040
Phone
(206) 790-1094
(206) 236-1836 (Fax)
(206) 236-1836 (Fax)
Personal information
See more information about RONALD BERENSON at radaris.comName
Address
Phone
7268 N Mercer Way, Mercer Island, WA 98040
7264 Mercer Way, Mercer Island, WA 98040
Organization information
See more information about RONALD BERENSON at bizstanding.comRonald Berenson MD
7264 N Mercer Way, Mercer Island, WA 98040
Industry:
Internist
Ronald Jay Berenson
Professional information
Methods And Device For Culturing Human Hematopoietic Cells And Their Precursors
US Patent:
5635387, Jun 3, 1997
Filed:
Apr 3, 1995
Appl. No.:
8/415752
Inventors:
Rui G. Fei - Seattle WA
Shelly Heimfeld - Woodinville WA
Billy W. Minshall - Mill Creek WA
Ronald J. Berenson - Mercer Island WA
Shelly Heimfeld - Woodinville WA
Billy W. Minshall - Mill Creek WA
Ronald J. Berenson - Mercer Island WA
Assignee:
CellPro, Inc. - Bothell WA
International Classification:
C12N 500, C12N 502, A61K 3514
US Classification:
435378
Abstract:
Methods for increasing the number of human hematopoietic precursor cells in vitro are provided. The methods generally comprise (a) separating human hematopoietic precursor cells from mature hematopoietic cells present in a blood product; (b) inoculating the separated precursor cells into a culture vessel containing a culture medium comprising a nutritive medium and a source of growth factors at a density of between 1. times. 10. sup. 3 cells/ml and 4. times. 10. sup. 6 cells/ml; and (c) culturing the cells under conditions and for a time sufficient to increase the number of precursor cells relative to the number of such cells present in the blood product. The culture medium may also include a suitable amount of microcarrier beads. Suitable blood products include bone marrow, umbilical cord blood, and peripheral blood. A device for carrying out such methods is also provided.
Method For Transdermal Iontophoretic Delivery Of Chelated Agents
US Patent:
2010027, Oct 28, 2010
Filed:
Jul 7, 2009
Appl. No.:
12/459862
Inventors:
Mir Imran - Los Altos Hills CA, US
Mir Hashim - Fremont CA, US
Sanjay Patel - Palo Alto CA, US
Ronald J. Berenson - Mercer Island WA, US
Mir Hashim - Fremont CA, US
Sanjay Patel - Palo Alto CA, US
Ronald J. Berenson - Mercer Island WA, US
International Classification:
A61K 33/42, A61K 33/26, A61P 7/06
US Classification:
424604, 424646
Abstract:
Embodiments provide devices, systems and methods for the transdermal delivery of chelated compounds. One embodiment provides a method for the iontophoretic transdermal delivery of a chelated iron complex for the treatment of anemia. A first patch comprising an active electrode and a chelated iron complex is applied to the skin; a second patch containing an electrode is also applied. An electrical current is then delivered to the skin from the active electrode. The chelated complex is transported across the skin via electromotive force from the current, with the iron being substantially chromogenically unreactive with the skin during transport so that there is little or no tattooing of the skin due to the formation of insoluble oxidative products. The complex is then dissociated by phagocytosis or related process to release the iron where it may be bound by transferrin or ferritin and carried to other sites for storage or metabolic use.
Compositions And Methods For Modulating The Activity Of Complement Regulatory Proteins On Target Cells
US Patent:
2010025, Oct 7, 2010
Filed:
Mar 31, 2010
Appl. No.:
12/751943
Inventors:
André Lieber - Seattle WA, US
Hongjie Wang - Seattle WA, US
Ronald Jay Berenson - Mercer Island WA, US
Darrick Carter - Seattle WA, US
Hongjie Wang - Seattle WA, US
Ronald Jay Berenson - Mercer Island WA, US
Darrick Carter - Seattle WA, US
Assignee:
UNIVERSITY OF WASHINGTON - Seattle WA
COMPLIMENT CORPORATION - Mercer Island WA
COMPLIMENT CORPORATION - Mercer Island WA
International Classification:
A61K 39/395, C07K 7/08, C07K 7/06, A61K 38/06, A61K 38/08, A61K 38/10, C07K 5/08, C07K 14/00, A61K 38/16, A61K 35/76, C12N 15/63, C40B 30/04, C07H 21/04, C07K 16/30, A61P 35/00
US Classification:
4241741, 530326, 530327, 530328, 530329, 530330, 530331, 530324, 514 193, 4241301, 4241781, 424 936, 4353201, 506 9, 536 231, 5303897
Abstract:
This invention relates to agents capable of reducing the activity, amount or density of complement regulatory proteins (CRPs) on target cells. The invention also provides methods of identification of such agents, methods of making, and uses thereof.
Activation And Expansion Of Cells
US Patent:
2005015, Jul 14, 2005
Filed:
Dec 2, 2004
Appl. No.:
11/001921
Inventors:
Ronald Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
C12N005/08
US Classification:
435372000
Abstract:
The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.
Methods For Restoring Or Enhancing T-Cell Immune Surveillance Following Naturally Or Artificially Induced Immunosuppression
US Patent:
2002001, Feb 14, 2002
Filed:
May 24, 2001
Appl. No.:
09/864930
Inventors:
Ronald Berenson - Mercer Island WA, US
International Classification:
C12N005/08, A61K045/00
US Classification:
435/372000, 424/093700, 424/144100
Abstract:
The present invention relates generally to methods for restoring or enhancing T-cell immune surveillance, and more particularly, to a method treating an immuno-compromised, immuno-deficient, or immuno-suppressed animal by infusion of peripheral blood lymphocytes, T-cells, or activated T-cells.
Activation And Expansion Of Cells
US Patent:
2005021, Sep 29, 2005
Filed:
Nov 8, 2004
Appl. No.:
10/984351
Inventors:
Ronald Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
C12N005/08
US Classification:
435372000
Abstract:
The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.
Maturation Of Antigen-Presenting Cells Using Activated T Cells
US Patent:
2003008, May 1, 2003
Filed:
Apr 29, 2002
Appl. No.:
10/136024
Inventors:
Ronald Berenson - Mercer Island WA, US
Mark Bonyhadi - Issaquah WA, US
Stewart Craig - Issaquah WA, US
Dale Kalamasz - Redmond WA, US
Tatsue Monji - Seattle WA, US
Mark Bonyhadi - Issaquah WA, US
Stewart Craig - Issaquah WA, US
Dale Kalamasz - Redmond WA, US
Tatsue Monji - Seattle WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
A61K048/00, C12N005/08
US Classification:
435/372000, 424/093210
Abstract:
The present invention relates to methods for maturing antigen-presenting cells, and more particularly, to methods for maturing dendritic cells. Methods for generating mature and/or maturing antigen-presenting cells in vitro and in vivo are disclosed. The present invention also relates to compositions of cells, including mature antigen-presenting cells and/or activated T cells and their use in generating immune responses in vivo, and inhibiting the development of or preventing infectious diseases and cancers.
T Cell Therapy For The Treatment Of Cachexia And Chronic Diseases
US Patent:
2005022, Oct 13, 2005
Filed:
Mar 28, 2005
Appl. No.:
11/091361
Inventors:
Mark Bonyhadi - Issaquah WA, US
Ronald Berenson - Mercer Island WA, US
Ronald Berenson - Mercer Island WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
A61K045/00, C12N005/08
US Classification:
424093700, 435372000
Abstract:
The present invention relates to compositions and methods for the use of T cells and more particularly, activated T cells, in the treatment and/or amelioration of diseases associated with a proinflammatory state, such as cachexia, chronic diseases such as chronic renal failure, and hepatitis.
Detection Of Short-Chain Fatty Acids In Biological Samples
US Patent:
2011003, Feb 10, 2011
Filed:
Jul 12, 2010
Appl. No.:
12/834720
Inventors:
Ronald J. Berenson - Mercer Island WA, US
Patrick Bobbitt - Seattle WA, US
Zhongping Lin - Wilimington DE, US
Patrick Bobbitt - Seattle WA, US
Zhongping Lin - Wilimington DE, US
Assignee:
HEMAQUEST PHARMACEUTICALS, INC. - Seattle WA
International Classification:
G01N 33/50
US Classification:
436129
Abstract:
Described herein is a method of detecting and/or quantifying analytes, such as short-chain fatty acids. Analysis for the presence and/or quantity of the small molecule can be performed on a biological sample from a subject. In some embodiments, a liquid chromatography/mass spectrometry (LC-MS/MS) instrumentation is combined with a solid-phase extraction (SPE). Methods of derivatization can also be incorporated with LC-MS/MS and SPE instrumentation to detect and quantify target analytes. In addition to derivation, methods of reconstituting derivatized molecules can also be incorporated with LC-MS/MS and SPE instrumentation to detect and quantify target analytes.
Activation And Expansion Of Cells
US Patent:
2003011, Jun 26, 2003
Filed:
Jun 28, 2002
Appl. No.:
10/187467
Inventors:
Ronald Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Chana - Issaquah WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
C12N005/08
US Classification:
435/372000
Abstract:
The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.