ROMAN J GIGER
Pharmacy in Ann Arbor, MI

License number
Michigan 5304000461
Issued Date
May 4, 2010
Expiration Date
Jun 30, 2017
Category
Pharmacy
Type
CS - Research Lab
Address
Address
Ann Arbor, MI 48109

Professional information

Roman Giger Photo 1

Nogo-Receptors And Methods Of Use

US Patent:
2009020, Aug 13, 2009
Filed:
Feb 24, 2009
Appl. No.:
12/391983
Inventors:
Roman J. Giger - Ann Arbor MI, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
C12N 5/06, C07H 21/00
US Classification:
435325, 536 235
Abstract:
Disclosed are compositions relating to the Nogo receptor (NgR) family as well as fragments, chimeras, and variants thereof. The invention provides polypeptides, nucleic acids, vectors, expression systems, and antibodies and antibody fragments related to the NgRs as well as uses thereof. Such uses include modulation neurite outgrowth in a subject and treatment of central nervous system disorders in a subject, as well as, methods of identifying and screening compounds that can be used for modulating neurite outgrowth in a subject or in treatment of central nervous system disorders in a subject.