DR. ROGER K KHOURI, MD
Medical Practice at 37 Ave, Miami, FL

6514200, Feb 4, 2003

May 17, 2000

09/572348

Roger K. Khouri - Key Biscayne FL

Brava, LLC - Coconut Grove FL

A61B 500

600300, 600 38, 600587, 128898, 128920, 606 6

A patient monitoring device includes a microprocessor controller having a clock circuit and memory coupled to one or more sensors physically carried by a medical appliance such that as the medical appliance is properly fitted to and worn by the patient, the sensors provide an electrical signal confirming that which may be then timed to provide data which confirms a patients compliance with a recommended protocol. By combining and correlating the sensor data with the clock or timer provided as part of the controller, a time chart of data may be created indicating when and for how long the patient actually wears the device. Additionally, other sensors may be used to collect data relating to various operational parameters of the device including the amount of negative pressure presented under a vacuum dome or other parameters related to the operation of the medical appliance itself, as desired.

6641527, Nov 4, 2003

Jun 11, 2001

09/878729

Roger K. Khouri - Key Biscayne FL

Brava, LLC - Miami FL

A61F 500

600 38, 601 14

A soft tissue expander comprises a frame comprised of inflatable members having in several embodiments a peripheral restrictor to force the frame to expand in only two dimensions. Various embodiments include frames arranged to be comprised of different polygonal shapes, frame members having internal mechanical restrictors, frames comprised of fusiform or cellular construction, and frames contained within two membranes that may also be filled with fluid.

6478656, Nov 12, 2002

Dec 1, 1998

09/203832

Roger K. Khouri - Key Biscayne FL

Brava, LLC - Coconut Grove FL

A41C 300

450 39, 450 1, 600 38

A soft tissue expander comprises a dome having a layer of memory material which transitions from a first, shallower, malleable configuration to a second, deeper configuration in response to its being heated to its transition temperature which is set at human body surface temperature. The second, deeper configuration is first “set” in the memory of the memory material so that the dome returns to it upon being heated by the body temperature of the patient. The memory material may be any one of the shape memory alloys, or plastic materials. The interior of the dome is adhered to the skin of the soft tissue to be expanded, such as through sticky layer of gel or surface tension provided by a thin layer of fluid. In one embodiment, a bra has a pair of domes for covering a patients breasts and which applies a tensile force thereon to thereby increase their size.

2008016, Jul 10, 2008

Jun 26, 2007

11/768902

Roger K. Khouri - Key Biscayne FL, US
Murat Kuru - Miami FL, US

A61M 1/00, A61M 5/00, A61M 39/22

604119, 604131, 604319, 251356

A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a helicoidal spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.

2005024, Nov 3, 2005

Apr 7, 2005

11/101240

Carlos Freyre - Miami FL, US
Roger Khouri - Key Biscayne FL, US

A61B019/00, A61H007/00, A61F005/00

601006000, 128898000

A dome for applying a vacuum to a patient's breast is comprised of a generally rigid dome capable of withstanding a pressure differential, with a rim and rim cushion underlying the rim of the dome for supporting a rim from the patient's skin surface. The rim may be generally wider than the dome in order to distribute the attendant forces across a greater surface and avoid tissue damage. A sticky sole underlies the rim cushion and seals the rim cushion to the patient's skin to thereby preserve the vacuum within the dome. The sticky sole may be comprised of any adhesive material or even be achieved through the use of an appropriate material for the rim cushion itself. A portable pump unit is connected to the domes and maintains the vacuum within the domes during a recommended protocol. By using the device in accordance with the prescribed protocol, the growth of cancer cells and tumors within the breasts are inhibited.

8360102, Jan 29, 2013

Dec 8, 2009

12/633442

Roger K. Khouri - Key Biscayne FL, US
Murat Kuru - Miami FL, US

Lipocosm LLC - Key Biscayne FL

F16K 11/00

137597, 604 31, 604247

A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2. 0 to 4. 0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.

8066691, Nov 29, 2011

Apr 21, 2006

11/409294

Roger K. Khouri - Key Biscayne FL, US

A61K 35/12

604522, 601 6, 601 11, 606201, 424 937, 514574

A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s) of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing rims for surrounding each of the breasts and a regulated pump. The method for preparing the soft tissue site, and enhancing fat graft results, entails application of the distracting force to the targeted soft tissue site for several weeks prior to the graft procedure. A related aspect of the invention includes following the preparation steps by transfer of fat from other areas of the subject to the subject's breast(s), and then reapplication of the distractive force to the breast(s) that received the autologous fat graft. Alternatively, fat from genetically related sources may be used, and the fat may be further processed prior to injection. Substantial breast augmentation, high rates of graft survival and negligible graft necrosis (data demonstrating 80% survival and only 20% necrosis is presented) or calcification result from the practice of these methods.

2004017, Sep 9, 2004

Mar 10, 2004

10/798739

George Hermann - Portola Valley CA, US
Jose de la Pena - Lomas Virreyes, MX
Roger de la Torre - Wentzville MO, US
Thomas Howell - Palo Alto CA, US
Roger Khouri - Key Biscayne FL, US
David Willis - Palo Alto CA, US
Michael Drews - Sacramento CA, US

Thomas J. Fogarty, M.D. - Portola Valley CA

A61B017/04

606/150000

Tissue approximation devices for the minimally invasive approximation of muscle or fascia, such as approximation of the rectus muscles in the abdomen (abdominoplasty), or hernia repair and other such applications using minimally invasive methods to access and perform the procedures thereby reducing or eliminating visible scars.