Inventors:
Robin David Grey Cooper - Indianapolis IN
Michael John Rodriguez - Indianapolis IN
Nancy June Snyder - Charlottesville IN
Mark James Zweifel - Indianapolis IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 3812, A61K 3808, C07K 700, C07K 900
Abstract:
The present invention is directed to amides of antibiotic A82846B (also known as chloroorienticin A), and of N. sup. 4 -derivatives of A82846B. The present amide compounds are useful as antibacterials, especially for the control of gram positive bacteria; the compounds are particularly useful for the control of resistant bacterial strains, such as vancomycin-resistant-enterococci ("VRE").