Roberto A Aponte
Nursing at Woodland Dr, Volo, IL
License number
Florida 349544
Issued Date
May 23, 2017
Effective Date
May 23, 2017
Expiration Date
May 31, 2018
Category
Health Care
Type
Certified Nursing Assistant
Address
Address
17572 W Woodland Dr, Volo, IL 60030
Phone
(224) 237-5344
Professional information
Enhancement Of Oral Bioavailability Of Non-Emulsified Formulations Of Prodrug Esters With Lecithin
US Patent:
2005011, May 26, 2005
Filed:
Dec 13, 2004
Appl. No.:
11/014798
Inventors:
Rajneesh Taneja - Libertyville IL, US
Dale Brinker - Antioch IL, US
Jacqueline Briskin - Buffalo Grove IL, US
Dilip Vishwasrao - Waukegan IL, US
Roberto Aponte - Grayslake IL, US
Pramod Gupta - Gurnee IL, US
Dale Brinker - Antioch IL, US
Jacqueline Briskin - Buffalo Grove IL, US
Dilip Vishwasrao - Waukegan IL, US
Roberto Aponte - Grayslake IL, US
Pramod Gupta - Gurnee IL, US
International Classification:
A61K031/685, A61K031/545, A61K031/57
US Classification:
514078000, 514200000, 514171000
Abstract:
A method for enhancing the oral bioavailability of a prodrug ester by formulating the ester as a non-emulsified formulation with lecithin; as well as a pharmaceutical composition of at least one antibiotic and lecithin in a non-emulsified formulation; a method of treating infections with the non-emulsified formulation, and a method for preparing tablets by direct compression of blends of drugs with lecithin are disclosed. Non-emulsified formulations include solids, tablets, capsules, lozenges, suspensions, elixirs and solutions, and exclude emulsions, liposomes, lipid matrix systems and micro-emulsions. A suitable prodrug ester is a cephalosporin β-lactam antibiotic such as cefditoren pivoxil, and a suitable non-emulsified formulation is a solid formulation.
Enhancement Of Oral Bioavailability Of Non-Emulsified Formulations Of Prodrug Esters With Lecithin
US Patent:
2003006, Mar 27, 2003
Filed:
May 28, 2002
Appl. No.:
10/156488
Inventors:
Rajneesh Taneja - Libertyville IL, US
Dale Brinker - Antioch IL, US
Jacqueline Briskin - Buffalo Grove IL, US
Dilip Vishwasrao - Waukegan IL, US
Roberto Aponte - Grayslake IL, US
Pramod Gupta - Gurnee IL, US
Dale Brinker - Antioch IL, US
Jacqueline Briskin - Buffalo Grove IL, US
Dilip Vishwasrao - Waukegan IL, US
Roberto Aponte - Grayslake IL, US
Pramod Gupta - Gurnee IL, US
International Classification:
A61K031/685, A61K031/56, A61K031/545
US Classification:
514/078000, 514/200000, 514/171000
Abstract:
A method for enhancing the oral bioavailability of a prodrug ester by formulating the ester as a non-emulsified formulation with lecithin; as well as a pharmaceutical composition of at least one antibiotic and lecithin in a non-emulsified formulation; a method of treating infections with the non-emulsified formulation, and a method for preparing tablets by direct compression of blends of drugs with lecithin are disclosed. Non-emulsified formulations include solids, tablets, capsules, lozenges, suspensions, elixirs and solutions, and exclude emulsions, liposomes, lipid matrix systems and micro-emulsions. A suitable prodrug ester is a cephalosporin -lactam antibiotic such as cefditoren pivoxil, and a suitable non-emulsified formulation is a solid formulation.