Inventors:
Robert Thornburg - Ames IA
Assignee:
Iowa State University Research Foundation, Inc. - Ames IA
International Classification:
C12N 1529, C12N 1562, C12N 1582, C12N 504, A01H 500
Abstract:
Provided herein are signal peptides, and constructs and vectors having signal peptides, as well as methods of using signal peptides to deliver proteins into secretory material. The invention facilitates the purification of recombinant proteins. Also provided are a new class of proteins called nectarins, from which the signal peptides may be derived. Additionally, the nectarins possess oxalate oxidase activity and have utility as agents for treating diseases or conditions relating to abnormal oxalate deposition or metabolism or as diagnostics for measuring oxalate concentrations in specimens.