ROBERT SUN
Accountancy in Natick, MA
License number
Massachusetts 32697
Issued Date
Oct 20, 2015
Expiration Date
Jun 30, 2017
Type
Certified Public Accountant
Address
Address
Natick, MA 01760
Professional information
1,4-Disubstituted Pyridazine Analogs There Of And Methods For Treating Smn-Deficiency-Related Conditions
US Patent:
2014005, Feb 20, 2014
Filed:
Aug 7, 2013
Appl. No.:
13/960917
Inventors:
Atwood Kim CHEUNG - Arlington MA, US
Donovan Noel CHIN - Lexington MA, US
Natalie DALES - Arlington MA, US
Aleem FAZAL - Burlington MA, US
Timothy Brian HURLEY - Boston MA, US
John KERRIGAN - Wakefield MA, US
Gary O'BRIEN - Maynard MA, US
Lei SHU - Woburn MA, US
Robert SUN - Natick MA, US
Moo Je SUNG - Belmont MA, US
Donovan Noel CHIN - Lexington MA, US
Natalie DALES - Arlington MA, US
Aleem FAZAL - Burlington MA, US
Timothy Brian HURLEY - Boston MA, US
John KERRIGAN - Wakefield MA, US
Gary O'BRIEN - Maynard MA, US
Lei SHU - Woburn MA, US
Robert SUN - Natick MA, US
Moo Je SUNG - Belmont MA, US
International Classification:
C07D 401/12, A61K 45/06, C07D 409/14, C07D 401/14, A61K 31/502, C07D 413/14, C07D 417/14, A61K 31/5377, C07D 403/12, A61K 31/551, C07D 471/08, C07D 471/10, C07D 471/04, C07D 403/14, C07D 403/10, C07D 487/10, C07D 487/04, C07D 237/20, C07D 401/04, C07D 405/14, A61K 31/506, A61K 31/501
US Classification:
5142102, 544238, 51425203, 51425204, 514249, 514248, 544237, 544114, 5142365, 51425205, 51425202, 514218, 540575, 544230, 51425206
Abstract:
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Heterocyclic Compounds And Use Thereof As Erk Inhibitors
US Patent:
2011003, Feb 17, 2011
Filed:
Jun 17, 2008
Appl. No.:
12/601476
Inventors:
Robert Sun - Natick MA, US
Alan B. Cooper - West Caldwell NJ, US
Yongqi Deng - Newton MA, US
Tong Wang - New Vernon NJ, US
Yang Nan - Malden MA, US
Hugh Y. Zhu - Warren NJ, US
Sobhana Babu Boga - Scotch Plains NJ, US
Xiaolei Gao - Bridgewater NJ, US
Joseph M. Kelly - Parlin NJ, US
Sunil Paliwal - Monroe Township NJ, US
Ronald J. Doll - Convent Station NJ, US
Neng-Yang Shih - Lexington MA, US
Alan B. Cooper - West Caldwell NJ, US
Yongqi Deng - Newton MA, US
Tong Wang - New Vernon NJ, US
Yang Nan - Malden MA, US
Hugh Y. Zhu - Warren NJ, US
Sobhana Babu Boga - Scotch Plains NJ, US
Xiaolei Gao - Bridgewater NJ, US
Joseph M. Kelly - Parlin NJ, US
Sunil Paliwal - Monroe Township NJ, US
Ronald J. Doll - Convent Station NJ, US
Neng-Yang Shih - Lexington MA, US
International Classification:
A61K 31/519, C07D 487/04, C07D 487/08, A61K 31/496, A61K 39/395, A61P 35/00, A61P 35/02
US Classification:
4241581, 544251, 514267, 51425216, 4241721
Abstract:
Disclosed are the ERK inhibitors of formula 1.0: [Formula (1.0)] and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
Substituted Carbamoylcycloalkyl Acetic Acid Derivatives As Nep
US Patent:
2012012, May 17, 2012
Filed:
Nov 10, 2011
Appl. No.:
13/293560
Inventors:
Rajeshri Ganesh KARKI - Somerville MA, US
Toshio KAWANAMI - Boston MA, US
Gary Michael KSANDER - Boston MA, US
Qian LIU - Malden MA, US
Muneto MOGI - Waltham MA, US
Nikolaus SCHIERING - Weil am Rhein, DE
Robert SUN - Natick MA, US
Toshio KAWANAMI - Boston MA, US
Gary Michael KSANDER - Boston MA, US
Qian LIU - Malden MA, US
Muneto MOGI - Waltham MA, US
Nikolaus SCHIERING - Weil am Rhein, DE
Robert SUN - Natick MA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
A61K 38/05, C07D 295/195, C07C 235/82, C07D 213/56, C07D 257/04, C07D 471/04, A61K 31/216, A61K 31/194, A61K 31/4418, A61K 31/41, A61K 31/437, A61P 9/12, A61P 3/10, A61P 3/04, A61P 9/04, A61P 9/00, A61P 9/10, A61P 13/12, A61P 1/16, A61P 9/06, A61P 5/42, A61P 27/06, A61P 15/00, A61P 11/06, A61P 29/00, A61P 35/02, A61P 25/08, A61P 25/24, A61P 25/18, A61P 1/00, A61P 3/00, C07D 207/16
US Classification:
514 18, 548533, 548540, 560 41, 562450, 546335, 548253, 546118, 514 201, 514530, 514563, 514357, 514381, 514303, 514 157, 514 164, 514 154, 514 19, 514 196, 514 177, 514 69
Abstract:
The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, B, X, m and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of compounds of the invention, and a combination of pharmacologically active agents and a compound of the invention.
Substituted Aminobutyric Derivatives As Neprilysin Inhibitors
US Patent:
2012025, Oct 4, 2012
Filed:
Jun 7, 2012
Appl. No.:
13/490562
Inventors:
Gary Mark Coppola - Budd Lake NJ, US
Yuki Iwaki - Tokyo, JP
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Yuki Iwaki - Tokyo, JP
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
A61K 31/197, C07C 235/74, C07C 235/12, C07C 235/82, C07D 303/46, A61K 31/336, C07D 307/68, A61K 31/341, C07D 333/38, A61K 31/381, C07D 213/81, A61K 31/44, C07D 239/28, A61K 31/505, C07D 231/14, A61K 31/415, C07D 207/34, A61K 31/40, C07D 233/90, A61K 31/4164, C07D 211/60, A61K 31/445, C07D 239/42, C07D 239/36, A61P 7/10, A61P 3/10, A61P 3/04, A61P 9/12, A61P 9/00, A61P 13/12, A61P 17/00, A61P 9/10, A61P 9/06, A61P 27/06, A61P 15/00, A61P 15/06, A61P 11/06, A61P 29/00, A61P 35/02, A61P 25/08, A61P 25/24, A61P 25/18, A61P 25/28, A61P 1/00, A61P 17/02, A61P 3/00, C07C 235/84
US Classification:
514274, 562450, 514563, 562444, 549549, 514475, 549484, 514471, 549 71, 514448, 546323, 514354, 544335, 514256, 5483741, 514406, 548533, 514423, 5483345, 514400, 546227, 514330, 544329, 544316
Abstract:
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R, R, R, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Imidazole Derivatives As Aldosterone Synthase Inhibitors
US Patent:
8575160, Nov 5, 2013
Filed:
Nov 29, 2010
Appl. No.:
13/511581
Inventors:
Robert Sun - Natick MA, US
Lauren G. Monovich - Belmont MA, US
Sylvie Chamoin - Saint Louis, FR
John Westbrook - Woodbridge CT, US
Lauren G. Monovich - Belmont MA, US
Sylvie Chamoin - Saint Louis, FR
John Westbrook - Woodbridge CT, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 487/04, A61K 31/4188, A61K 31/428
US Classification:
5142332
Abstract:
The present invention provides a compound of formula (I) or pharmaceutically acceptable salt thereof, wherein the variables R, R, R, R, R, Rand p are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Substituted Aminopropionic Derivatives As Neprilysin Inhibitors
US Patent:
2013009, Apr 18, 2013
Filed:
Nov 29, 2012
Appl. No.:
13/688630
Inventors:
NOVARTIS AG - Basel, CH
Yuki Iwaki - Tokyo, JP
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Yuki Iwaki - Tokyo, JP
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
C07D 265/30, A61K 31/505, A61K 31/421, A61K 31/41, A61K 45/00, C07C 237/16, A61K 31/216, A61K 31/197, C07D 239/28, C07D 263/32, C07D 257/04, C07C 271/22, A61K 31/5375, A61K 31/325
US Classification:
5142378, 514272, 514374, 514381, 514479, 514487, 514507, 514562, 514563, 544168, 544332, 548236, 548253, 560 13, 560 27, 560312, 562430, 562448
Abstract:
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, B, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Substituted Aminopropionic Derivatives As Neprilysin Inhibitors
US Patent:
8394853, Mar 12, 2013
Filed:
May 27, 2010
Appl. No.:
12/788766
Inventors:
Gary Mark Coppola - Budd Lake NJ, US
Yuki Iwaki - Cambridge MA, US
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Yuki Iwaki - Cambridge MA, US
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/235, C07C 229/34
US Classification:
514533, 514563, 546335, 560 41
Abstract:
The present invention provides a compound of formula I′;.
Substituted Aminobutyric Derivatives As Neprilysin Inhibitors
US Patent:
8263629, Sep 11, 2012
Filed:
May 27, 2010
Appl. No.:
12/788794
Inventors:
Gary Mark Coppola - Budd Lake NJ, US
Yuki Iwaki - Cambridge MA, US
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Yuki Iwaki - Cambridge MA, US
Rajeshri Ganesh Karki - Somerville MA, US
Toshio Kawanami - Boston MA, US
Gary Michael Ksander - Amherst NH, US
Muneto Mogi - Waltham MA, US
Robert Sun - Natick MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/42, A61K 31/4245, A61K 31/41, C07D 271/04, C07D 271/06, C07D 271/08, C07D 271/10, C07D 263/30, C07D 261/06, C07D 257/02
US Classification:
514364, 514374, 514378, 514381, 548131, 548143, 548215, 548240, 548250
Abstract:
The present invention provides a compound of formula I′;.
Compounds That Are Erk Inhibitors
US Patent:
8546404, Oct 1, 2013
Filed:
Jun 5, 2007
Appl. No.:
11/810282
Inventors:
Alan B. Cooper - West Caldwell NJ, US
Yongqi Deng - Newton MA, US
Neng-Yang Shih - Lexington MA, US
Hugh Y. Zhu - Scotch Plains NJ, US
Robert Sun - Natick MA, US
Joseph M. Kelly - Parlin NJ, US
Ronald J. Doll - Convent Station NJ, US
Yang Nan - Malden MA, US
Tong Wang - Cambridge MA, US
Jagdish A. Desai - Monroe Township NJ, US
James J-S Wang - Westfield NJ, US
Youhao Dong - Cambridge MA, US
Vincent S. Madison - Mountain Lakes NJ, US
Li Xiao - Cranbury NJ, US
Alan W. Hruza - Hackettstown NJ, US
M. Arshad Siddiqui - Newton MA, US
Ahmed A. Samatar - West Windsor NJ, US
Sunil Paliwal - Monroe Township NJ, US
Azim Alan Celebi - Clark NJ, US
Yiji Wu - Scotch Plains NJ, US
Sobhana Babu Boga - Scotch Plains NJ, US
Abdul-Basit Alhassan - Scotch Plains NJ, US
Xiaolei Gao - Scotch Plains NJ, US
Liang Zhu - Somerville MA, US
Mehul Patel - Waltham MA, US
Yongqi Deng - Newton MA, US
Neng-Yang Shih - Lexington MA, US
Hugh Y. Zhu - Scotch Plains NJ, US
Robert Sun - Natick MA, US
Joseph M. Kelly - Parlin NJ, US
Ronald J. Doll - Convent Station NJ, US
Yang Nan - Malden MA, US
Tong Wang - Cambridge MA, US
Jagdish A. Desai - Monroe Township NJ, US
James J-S Wang - Westfield NJ, US
Youhao Dong - Cambridge MA, US
Vincent S. Madison - Mountain Lakes NJ, US
Li Xiao - Cranbury NJ, US
Alan W. Hruza - Hackettstown NJ, US
M. Arshad Siddiqui - Newton MA, US
Ahmed A. Samatar - West Windsor NJ, US
Sunil Paliwal - Monroe Township NJ, US
Azim Alan Celebi - Clark NJ, US
Yiji Wu - Scotch Plains NJ, US
Sobhana Babu Boga - Scotch Plains NJ, US
Abdul-Basit Alhassan - Scotch Plains NJ, US
Xiaolei Gao - Scotch Plains NJ, US
Liang Zhu - Somerville MA, US
Mehul Patel - Waltham MA, US
Assignee:
Merck Sharp & Dohme - Rahway NJ
International Classification:
A01N 43/54, C07D 239/42, C07D 401/04
US Classification:
514256, 514247, 514277, 514396, 544315, 546 1, 546184, 5463611, 5483561, 5483601
Abstract:
Disclosed are the ERK inhibitors of formula 1. 0:.