Inventors:
Stavros Manolagas - Little Rock AR, US
Robert Jilka - Little Rock AR, US
Robert Weinstein - Little Rock AR, US
Teresita Bellido - Little Rock AR, US
Donald Bodenner - Little Rock AR, US
Stavroula Kousteni - Little Rock AR, US
Assignee:
The Board of Trustees of the University of Arkansas - Little Rock AR
International Classification:
G01N033/53, G01N033/567, A61K031/56
Abstract:
The invention as disclosed provides a method to increase bone mass without compromising bone strength or quality, through the administration to a host of a compound that binds to the estrogen or androgen receptor without causing hormonal transcriptional activation.