Inventors:
Ernest G. Hope - Portola Valley CA, US
Robert Negrin - Stanford CA, US
Assignee:
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - Palo Alto CA
International Classification:
A61K 39/00, A01N 1/00, C12N 5/02, G01N 33/53, C07K 7/06, C07K 16/42, A61P 35/04, C12N 5/00, C07K 16/00, A61K 38/02, C12P 21/06, C12N 15/00
US Classification:
4242741, 435 11, 435375, 4353201, 4242771, 435 691, 435 72, 514 2, 530328, 5303879, 5303872, 435325
Abstract:
This invention concerns novel compositions and methods for for the protection of organs and cells from damage caused by activated lymphocytes, NK-cells and NK-like cells, more particularly compositions and methods for the protection of vascular endothelial cells from immune system-mediated damage.