Robert S Burgess
Social Work at Old Clf Rd, San Diego, CA
License number
Colorado 989921
Issued Date
Jun 20, 1992
Renew Date
Sep 1, 2015
Expiration Date
Aug 31, 2017
Type
Licensed Clinical Social Worker
Address
Address
5027 Old Cliffs Rd, San Diego, CA 92120
Professional information
Gene Targeting Methods And Vectors
US Patent:
2003002, Jan 30, 2003
Filed:
Jun 26, 2002
Appl. No.:
10/185980
Inventors:
Robert Marshall Burgess - San Diego CA, US
Henry Ji - San Diego CA, US
Henry Ji - San Diego CA, US
International Classification:
C12Q001/68, C12N015/00
US Classification:
435/006000, 435/320100, 800/013000
Abstract:
Methods and vectors are provided for the specific alteration of particular genetic loci in eukaryotic cells. One method includes the utilization of positive-positive selection (PPS) DNA vectors for the purpose of creating and identifying cells which have vector sequences integrated into the host cell genome via site-specific homologous recombination. The method also comprises the utilization of sequences encoding in vivo detectable markers for the identification of cells which have exogenous vector sequences integrated into the genome of the host cell, either via site-specific homologous recombination or nonhomologous recombination or insertion. The invention also includes vectors for creating modifications in eukaryotic cells.
Gene Targeting Methods And Vectors
US Patent:
2004021, Oct 28, 2004
Filed:
May 19, 2004
Appl. No.:
10/850293
Inventors:
Robert Burgess - San Diego CA, US
Henry Ji - San Diego CA, US
Henry Ji - San Diego CA, US
Assignee:
GENOME BIOSCIENCES, LLC
International Classification:
C12Q001/68, C12N015/85
US Classification:
435/006000, 435/455000
Abstract:
Methods and vectors are provided for the specific alteration of particular genetic loci in eukaryotic cells. One method includes the utilization of positive-positive selection (PPS) DNA vectors for the purpose of creating and identifying cells which have vector sequences integrated into host cell genome via site-specific homologous recombination. The method also comprises the utilization of sequences encoding in vivo detectable markers for the identification of cells which have exogenous vector sequences integrated into the genome of the host cell, either via site-specific homologous recombination or nonhomologous recombination or insertion. The invention also includes vectors for creating modifications in eukaryotic cells.