Inventors:
Robert Kaltenbach III - Wilmington DE, US
George Trainor - Wilmington DE, US
International Classification:
A61K031/675, A61K031/5375, A61K031/192, C07D265/30
US Classification:
514/090000, 514/239500, 514/570000, 544/157000, 544/171000, 562/491000
Abstract:
The present invention describes novel halogenated triphenylethylene derivatives, or pharmaceutically acceptable prodrug or salt forms thereof, as selective estrogen receptor modulators for the treatment of and/or prevention of breast, uterine, ovarian, prostrate and colon cancer, osteoporosis, cardiovascular disease, and benign proliferative disorders, as well as methods for making the compounds and pharmaceutical compositions of this invention.