ROBERT R PETERS
Barber in Boston, MA
License number
Massachusetts 702800
Issued Date
Jun 3, 2010
Expiration Date
Dec 31, 2017
Type
Apprentice Barber
Address
Address
Boston, MA 02126
Professional information
Director Of Sales At Pragmatic Works
Position:
Director of Sales at Pragmatic Works
Location:
Greater Boston Area
Industry:
Information Technology and Services
Work:
Pragmatic Works
since Sep 2008
-
Director of Sales
Quest Software
May 2005 - Aug 2008
-
Regional Sales Manager
Systems For Factor Viii Processing And Methods Thereof
US Patent:
2013028, Oct 24, 2013
Filed:
Jul 11, 2011
Appl. No.:
13/809285
Inventors:
Robert T. Peters - West Roxbury MA, US
Susan C. Low - Pepperell MA, US
Susan C. Low - Pepperell MA, US
Assignee:
Biogen Idec Hemophilia Inc. - Waltham MA
International Classification:
C07K 14/755
US Classification:
530383, 435 696, 435358, 435334, 435369, 435352, 4353201
Abstract:
The present invention provides methods of reducing nonprocessed Factor VIII or a chimeric polypeptide comprising Factor VIII comprising co-transfecting in a host cell a polynucleotide encoding Factor VIII with a polynucleotide encoding a protein convertase, where the endogenous processing enzymes of the host cell are insufficient to convert all of the Factor VIII to its processed isoform; expressing a proprotein convertase from a second polynucleotide in the host cell; and reducing the nonprocessed Factor VIII by processing with said proprotein convertase.
Methods For Chemically Synthesizing Immunoglobulin Chimeric Proteins
US Patent:
2011015, Jun 30, 2011
Filed:
Oct 22, 2010
Appl. No.:
12/910265
Inventors:
Adam R. MEZO - Waltham MA, US
Robert T. Peters - West Roxbury MA, US
Robert T. Peters - West Roxbury MA, US
International Classification:
C12P 21/00, C07K 19/00, C07K 16/00
US Classification:
435 696, 5303873, 5303919, 530358, 530351
Abstract:
The invention provides methods of chemically synthesizing chimeric proteins comprising at least a portion of an immunoglobulin constant region and a biologically active molecule.
Inhibition Of Drug Binding To Serum Albumin
US Patent:
2005003, Feb 17, 2005
Filed:
May 6, 2004
Appl. No.:
10/841949
Inventors:
Alan Bitonti - Acton MA, US
Vito Palombella - Needham MA, US
James Stattel - Leominster MA, US
Robert Peters - West Roxbury MA, US
Vito Palombella - Needham MA, US
James Stattel - Leominster MA, US
Robert Peters - West Roxbury MA, US
International Classification:
A61K031/00
US Classification:
514001000
Abstract:
The invention relates to improved therapeutics for treating diseases or conditions that provide greater bioavailabilty and more predictable dosing. The invention relates to a chimeric protein comprised of a biologically active molecule linked to an Fc fragment of an immunoglobulin, wherein the chimeric protein binds less serum albumin compared to the same biologically active molecule of the chimeric protein not linked to an Fc fragment of an immunoglobulin. The invention also relates to a method of treating a disease or condition said method comprising administering a chimeric protein comprising a biologically active molecule linked to an Fc fragment of an immunoglobulin, wherein the chimeric protein binds less serum albumin compared to the same biologically active molecule of the chimeric protein not linked to an Fc fragment of an immunoglobulin
Factor Viii-Fc Chimeric And Hybrid Polypeptides, And Methods Of Use Thereof
US Patent:
2013027, Oct 17, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/793783
Inventors:
Susan Low - Pepperill MA, US
Alan J. Bitonti - Acton MA, US
Glenn Pierce - Rancho Santa Fe CA, US
Alvin Luk - Boston MA, US
Haiyan Jiang - Belmont MA, US
Byron McKinney - San Diego CA, US
Matt Ottmer - Newton MA, US
Jurg Sommer - Wayland MA, US
Karen Nugent - Princes Risborough, GB
Lian Li - Lexington MA, US
Robert Peters - West Roxbury MA, US
Alan J. Bitonti - Acton MA, US
Glenn Pierce - Rancho Santa Fe CA, US
Alvin Luk - Boston MA, US
Haiyan Jiang - Belmont MA, US
Byron McKinney - San Diego CA, US
Matt Ottmer - Newton MA, US
Jurg Sommer - Wayland MA, US
Karen Nugent - Princes Risborough, GB
Lian Li - Lexington MA, US
Robert Peters - West Roxbury MA, US
International Classification:
A61K 38/37
US Classification:
514 141, 514 135
Abstract:
The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
Clotting Factor-Fc Chimeric Proteins To Treat Hemophilia
US Patent:
2013027, Oct 17, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/792889
Inventors:
Robert T. PETERS - West Roxbury MA, US
Alan J. BITONTI - Acton MA, US
Alan J. BITONTI - Acton MA, US
Assignee:
SYNTONIX PHARMACEUTICALS, INC. - Waltham MA
International Classification:
C07K 16/18
US Classification:
4241341, 536 234, 4353201, 435328, 435 696
Abstract:
The invention relates to a chimeric protein comprising at least one clotting factor and at least a portion of an immunoglobulin constant region. The invention relates to a method of treating a hemostatic disorder comprising administering a therapeutically effective amount of a chimeric protein wherein the chimeric protein comprises at least one clotting factor and at least a portion of an immunoglobulin constant region.
Methods For Chemically Synthesizing Immunoglobulin Chimeric Proteins
US Patent:
7381408, Jun 3, 2008
Filed:
May 6, 2004
Appl. No.:
10/842054
Inventors:
Adam R. Mezo - Waltham MA, US
Robert T. Peters - West Roxbury MA, US
Robert T. Peters - West Roxbury MA, US
Assignee:
Syntonix Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 39/00, C07K 1/00, C07K 1/02, C07K 1/03
US Classification:
4241331, 530333, 530334, 530338
Abstract:
The invention provides methods of chemically synthesizing chimeric proteins comprising at least a portion of an immunoglobulin constant region and a biologically active molecule.
Immunoglobulin Chimeric Monomer-Dimer Hybrids
US Patent:
7404956, Jul 29, 2008
Filed:
May 6, 2004
Appl. No.:
10/841250
Inventors:
Robert T. Peters - West Roxbury MA, US
Adam R. Mezo - Waltham MA, US
Daniel S. Rivera - Providence RI, US
Alan J. Bitonti - Acton MA, US
Susan C. Low - Pepperell MA, US
Adam R. Mezo - Waltham MA, US
Daniel S. Rivera - Providence RI, US
Alan J. Bitonti - Acton MA, US
Susan C. Low - Pepperell MA, US
Assignee:
Syntonix Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 39/00, C07K 16/00, C07K 1/00, C07K 14/00, C12P 21/08
US Classification:
4241781, 5303871, 5303873, 5303917, 530402
Abstract:
The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Pc5 As A Factor Ix Propeptide Processing Enzyme
US Patent:
7795400, Sep 14, 2010
Filed:
Jun 22, 2009
Appl. No.:
12/489391
Inventors:
Robert T. Peters - West Roxbury MA, US
Alan J. Bitonti - Acton MA, US
Alan J. Bitonti - Acton MA, US
Assignee:
Syntonix Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 38/48, C12Q 1/00, C12N 9/00
US Classification:
530384, 435 4, 435183
Abstract:
Compositions and methods for preparing Factor IX, Factor IX-containing fusion proteins, and Factor IX-containing conjugates with processing of Factor IX propeptide by PC5, are provided. In one embodiment PC5 is used to process a precursor polypeptide for a Factor IX-Fc monomer-dimer hybrid.
Methods For Chemically Synthesizing Immunoglobulin Chimeric Proteins
US Patent:
7820162, Oct 26, 2010
Filed:
Apr 9, 2008
Appl. No.:
12/100183
Inventors:
Adam R. Mezo - Waltham MA, US
Robert T. Peters - West Roxbury MA, US
Robert T. Peters - West Roxbury MA, US
Assignee:
Syntonix Pharmaceuticals, Inc. - Waltham MA
International Classification:
C07K 14/00
US Classification:
4241331, 530333, 530334, 530338, 530350, 530408
Abstract:
The invention provides methods of chemically synthesizing chimeric proteins comprising at least a portion of an immunoglobulin constant region and a biologically active molecule.