Inventors:
Paula Shadle - Lafayette CA, US
John C. Erickson - Research Triangle Park NC, US
Robert G. Scott - King of Prussia PA, US
Thomas M. Smith - King of Prussia PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
B01D 15/08, B01D 15/32, C07K 16/00, C07K 1/00
US Classification:
210635, 210656, 5303871, 5303905, 530413, 530417
Abstract:
This invention relates to the application of hydrophobic interaction chromatography combination chromatography to the purification of antibody molecule proteins. The questions raised in reexamination request, 09/006,966 filed Mar. 12, 2004 have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U. S. C. 307 as provided in 37 CFR 1. 570()().