ROBERT MENESES JR
Vehicle Board in Delaware
License number
Pennsylvania MV025770L
Category
Vehicle Board
Type
Vehicle Salesperson
Address
Address
2
Delaware
Wayne, PA 19087
Wayne, PA 19087
Professional information
Protease Inhibitors
US Patent:
2003011, Jun 19, 2003
Filed:
Oct 17, 2002
Appl. No.:
10/258053
Inventors:
Maxwell Cummings - Strafford PA, US
Robert Marquis Jr - Wayne PA, US
Yu Ru - Wayne PA, US
Scott Thompson - Phoenixville PA, US
Daniel Veber - Ambler PA, US
Dennis Yamashita - Wayne PA, US
Robert Marquis Jr - Wayne PA, US
Yu Ru - Wayne PA, US
Scott Thompson - Phoenixville PA, US
Daniel Veber - Ambler PA, US
Dennis Yamashita - Wayne PA, US
International Classification:
A61K031/55, C07D413/02, C 07D 4 3/02, C07D223/12
US Classification:
514/212030, 514/212080, 540/524000, 540/527000
Abstract:
The present invention provides methods which use 4-amino-azepan-3-one protease inhibitors of cathepsin S in the treatment of diseases in which cathepsin S is implicated, especially treatment or prevention of autoimmune disease; treatment or prevention of a disease state caused by the formation of atherosclerotic lesions and complications arising therefrom; and diseases requiring inhibition, for therapy, of a class II MHC-restricted immune response, inhibition of an asthmatic response, inhibition of an allergic response, inhibition of immune response against a transplanted organ or tissue, or inhibition of elastase activity in atheroma, and novel compounds for use therewith.