Inventors:
Robert B. Morris - Mill Valley CA
Roy Cronnelly - Pacifica CA
Ronald Dean Miller - Greenbrae CA
Assignee:
The Regents of the University of California - Berkeley CA
International Classification:
A61K 3144
Abstract:
A composition is provided which includes a balanced combination of an edrophonium component and an atropine component. A preferred embodiment has 0. 5 mg of edrophonium chloride and 8 micrograms of atropine sulfate, with respect to patient weight. The inventive composition is useful to antagonize nondepolarizing blockade during medical treatment when muscle relaxation is no longer necessary, provides extremely rapid onset of action and results in minimal heart rate changes.