Inventors:
Rudolph Neri - Hawthorne NJ
Robert J. Spiegel - Westfield NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 3156, A61K 4506, A61K 31135, A61K 3116
Abstract:
A method of treating gynecomastia in noncastrated patients being treated with an antiandrogen for androgen-dependent diseases such as benign prostatic hypertrophy, who are in need of such treating comprising administering to such patients therapeutically effective amounts of an antiandrogen, e. g. , flutamide, in association with an antiestrogen, e. g. , Tamoxifen, or an aromatase inhibitor such as 4-hydroxyadrostenedione is disclosed.