ROBERT J WINCHESTER, M.D.
Osteopathic Medicine at 168 St, New York, NY
License number
New York 097730
Category
Osteopathic Medicine
Type
Rheumatology
Address
Address
622 W 168Th St P&S 10-432, New York, NY 10032
Phone
(212) 305-8250
(212) 305-4943 (Fax)
(212) 305-4943 (Fax)
Personal information
See more information about ROBERT J WINCHESTER at radaris.comName
Address
Phone
4701 Perry Ct, Lewiston, NY 14092
51 Hill St, Alplaus, NY 12008
60 E End Ave APT 42B, New York, NY 10028
3957 S Clifford Ave, Bemus Point, NY 14712
935 Westholm Rd, Schenectady, NY 12309
Professional information
See more information about ROBERT J WINCHESTER at trustoria.com
Dr. Robert J Winchester, New York NY - MD (Doctor of Medicine)
Dr. Robert J Winchester, New York NY - MD (Doctor of Medicine)
Specialties:
Rheumatology
Address:
630 W 168Th St SUITE 4-477, New York 10032
(212) 305-7226 (Phone)
NEW YORK PRESBYTERIAN HOSPITAL
622 W 168Th St, New York 10032
(212) 746-3600 (Phone), (212) 342-2717 (Fax)
622 W 168Th St, New York 10032
(212) 305-8250 (Phone), (212) 305-4943 (Fax)
(212) 305-7226 (Phone)
NEW YORK PRESBYTERIAN HOSPITAL
622 W 168Th St, New York 10032
(212) 746-3600 (Phone), (212) 342-2717 (Fax)
622 W 168Th St, New York 10032
(212) 305-8250 (Phone), (212) 305-4943 (Fax)
Conditions:
Arthritis, Behçet's Disease, Dermatomyositis, Fibromyalgia, Giant Cell Arteritis, Gout, Osteoarthritis, Patellofemoral Pain Syndrome or Knee Pain, Polymyalgia Rheumatica (PMR), Polymyositis, Rheumatoid Arthritis, Sjögren's Syndrome, Still's Disease, Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Vasculitis, Wegener's Granulomatosis
Certifications:
Internal Medicine, 1972, Rheumatology, 1980
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
J & S Weill M C Cornell Univ
Graduated: 1963
New York Hospital
J & S Weill M C Cornell Univ
Graduated: 1963
New York Hospital
Robert Joseph Winchester, New York NY
Robert Joseph Winchester, New York NY
Specialties:
Internal Medicine, Rheumatology, Medical Genetics
Work:
Columbia University
630 W 168Th St, New York, NY 10032
630 W 168Th St, New York, NY 10032
Education:
Cornell University (1963)
Uses Of Inhibitors For The Activation Of Cxcr4 Receptor By Sdf-1 In Treating Rheumatoid Arthritis
Uses Of Inhibitors For The Activation Of Cxcr4 Receptor By Sdf-1 In Treating Rheumatoid Arthritis
US Patent:
2005020, Sep 15, 2005
Filed:
Nov 8, 2004
Appl. No.:
10/984482
Inventors:
Robert Winchester - New York NY, US
Tetsunori Seki - Roosevelt Island NY, US
Percio Gulko - Riverdale NY, US
Tetsunori Seki - Roosevelt Island NY, US
Percio Gulko - Riverdale NY, US
International Classification:
A61K039/395
US Classification:
424133100, 424144100, 424141100
Abstract:
This invention provides a method for treating rheumatoid arthritis or other forms of inflammatory arthritis which comprises administering to a subject an amount of an agent effective to inhibit the activation of the CXCR4 receptor by SDF-1. This invention further provides a composition for treating rheumatoid arthritis comprising an effective amount of an agent capable of inhibiting the activation of the CXCR4 receptor by SDF-1 and a pharmaceutically acceptable carrier. This invention also provides a method for determining whether an agent is capable of inhibiting the activation of the CXCR4 receptor by SDF-1 comprising: (a) contacting cells expressing the CXCR4 receptor in the presence of SDF-1 with the agent under conditions permitting activation of the CXCR4 receptor by SDF-1 if the agent is absent; and (b) determining whether the amount of activation of the CXCR4 receptor by SDF-1 is decreased in the presence of the agent relative to the amount of activation in its absence, such a decrease indicating that the agent is capable of inhibiting the activation of the CXCR4 receptor by SDF-1. Finally, this invention provides agents identified by such a method.
Use Of Inhibitors Of The Activation Of Cxcr4 Receptor By Sdf-1 In Treating Rheumatoid Arthritis
Use Of Inhibitors Of The Activation Of Cxcr4 Receptor By Sdf-1 In Treating Rheumatoid Arthritis
US Patent:
2002003, Apr 4, 2002
Filed:
Jan 31, 2001
Appl. No.:
09/773876
Inventors:
Robert Winchester - New York NY, US
Tetsunori Seki - Roosevelt Island NY, US
Percio Gulko - Riverdale NY, US
Tetsunori Seki - Roosevelt Island NY, US
Percio Gulko - Riverdale NY, US
International Classification:
A61K038/17, A61K039/395
US Classification:
514/002000, 424/142100, 424/133100
Abstract:
This invention provides a method for treating rheumatoid arthritis or other forms of inflammatory arthritis which comprises administering to a subject an amount of an agent effective to inhibit the activation of the CXCR4 receptor by SDF-1. This invention further provides a composition for treating rheumatoid arthritis comprising an effective amount of an agent capable of inhibiting the activation of the CXCR4 receptor by SDF-1 and a pharmaceutically acceptable carrier. This invention also provides a method for determining whether an agent is capable of inhibiting the activation of the CXCR4 receptor by SDF-1 comprising: (a) contacting cells expressing the CXCR4 receptor in the presence of SDF-1 with the agent under condition permitting activation of the CXCR4 receptor by SDF-1 if the agent is absent; and (b) determining whether the amount of activation of the CXCR4 receptor by SDF-1 is decreased in the presence of the agent relative to the amount of activation in its absence, such a decrease indicating that the agent is capable of inhibiting the activation of the CXCR4 receptor by SDF-1. Finally, this invention provides agents identified by such a method.