Inventors:
Herman W. Schlameus - San Antonio TX
William C. Fox - San Antonio TX
Donald J. Mangold - San Antonio TX
Robert G. Triplett - Dallas TX
George R. Holt - San Antonio TX
Thomas B. Aufdemorte - Lakeway TX
Assignee:
Southwest Research Institute - San Antonio TX
International Classification:
A61K 914
Abstract:
Osteoprogenitor cells encapsulated in alginate and alternatively, additionally encapsulated in poly-L-lysine and/or agarose promote regeneration of bone at the site of implantation. The present invention provides a composition comprising osteoprogenitor cells embedded or encapsulated in alginate and the use of said microcapsules for the facilitation of bone regeneration.