Inventors:
Wyndham Wilson - Washington DC, US
Robert E. Wittes - New York NY, US
Antonio Tito Fojo - Rockville MD, US
Susan Bates - Bethesda MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 31/335
Abstract:
The present invention is a method of treatment for a patient with cancer. In particular, it is a method of treating patients having lymphomas and breast cancer using the microtubule agent, Taxol. The present method of administration, serves to prevent or retard the adverse side effects associated with Taxol and reduces the chances of a patient developing mdr Taxol resistance. The novel method of treatment provides a low-dose, long-term exposure to Taxol in a patient.