Inventors:
Anthony J. Bauer - Pittsburgh PA, US
Gisela Bruenagel - Pittsburgh PA, US
Robert H. Getzenberg - Lutherville MD, US
Robert E. Schoen - Pittsburgh PA, US
Assignee:
University of Pittsburgh - Pittsburgh PA
International Classification:
C07K 16/18
US Classification:
5303879, 53038826, 5303888, 530328, 530350
Abstract:
Proteins useful in the diagnosis of proliferative disorders of the colon are present in nuclear matrix protein preparations and can be characterized by molecular weight, isoelectric point, and amino acid sequence. The proteins may be identified, for example, by 2D-gel electrophoresis or by specific binding partners, such as antibodies.