ROBERT DOUGLAS WHITE, PT,CHT
Restorative Service Providers at El Camino Real, Palo Alto, CA

7682837, Mar 23, 2010

Aug 7, 2001

09/923752

Maneesh Jain - San Francisco CA, US
Robert L. White - Stanford CA, US
Lester A. Roberts - Palo Alto CA, US

Board of Trustees of Leland Stanford Junior University - Stanford CA

G01N 33/551, C12Q 1/00

436526, 436518, 436149, 436150, 436151, 435 4, 435 6, 435 71, 4352871, 4352872, 2041828, 204299, 428 653, 428694, 428900, 428141, 427128, 427129, 427130, 427131

The invention includes devices and methods for forming random arrays of magnetic particles, arrays formed using these devices and methods, and to methods of using the arrays. The invention provides an assembly (chip) with magnetic domains that produce localized magnetic fields capable of immobilizing magnetic particles such as commercially available magnetic beads. Probe or sensor molecules can be coupled to the beads, which are then dispersed on the assembly, forming a random order array. The arrays can be used for analyzing samples, targets, and/or the interaction between samples and targets. The invention finds particular use in processes such as high-throughput genotyping and other nucleic acid hybridization-based assays.

8318093, Nov 27, 2012

May 17, 2007

11/804583

Shan X. Wang - Portola Valley CA, US
Robert L. White - Stanford CA, US
Chris D. Webb - Scotts Valley CA, US
Guanxiong Li - Stanford CA, US

The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA

G01N 1/36

422 50

Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

7682838, Mar 23, 2010

Nov 9, 2007

11/938187

Shan X. Wang - Portola Valley CA, US
Robert L. White - Stanford CA, US
Chris D. Webb - Scotts Valley CA, US
Guanxiong Li - Stanford CA, US

The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA

G01N 33/543, G01N 1/36

436526, 436518, 422 50, 422 98, 422276, 365173, 209214, 210222, 210223

Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

7729768, Jun 1, 2010

Mar 20, 2006

11/385986

Robert White - Stanford CA, US
George Savage - Portola Valley CA, US
Mark Zdeblick - Portola Valley CA, US

Proteus Biomedical, Inc. - Redwood City CA

A61N 1/00

607 35, 310319, 310354, 310367

Implantable cardiac motion powered piezoelectric energy sources are provided. An aspects of embodiments of the subject implantable energy sources is that they include a piezoelectric transducer that converts cardiac mechanical energy to electrical energy. The subject energy sources find use in a variety of applications, including providing power to a wide range of implantable devices.

2009010, Apr 23, 2009

Sep 19, 2008

12/234506

Shan X. Wang - Portola Valley CA, US
Sebastian J. Osterfeld - Menlo Park CA, US
Heng Yu - Mountain View CA, US
Nader Pourmand - San Mateo CA, US
Robert L. White - Stanford CA, US

G01N 33/00, G01N 27/00, B01J 19/00

436 86, 436151, 436 94, 422 681

Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.

5587223, Dec 24, 1996

Jun 30, 1994

8/270201

Robert L. White - Stanford CA

Board of Trustees Leland Stanford, Jr. University - Stanford CA

G11B 566, B32B 300

428195

Magnetic recording media comprising an ordered, ultra-high density array of 500. ANG. diameter circular magnetic thin film islands on a substrate. The magnetic material supports magnetization perpendicular to the film plan, and each circular island comprises a single magnetic domain and a single information storage bit. An areal bit density of 10. sup. 11 bits/in. sup. 2 can be achieved by such an array. The magnetic array is generated using a single level mask comprised of a self-ordering polymer array, either an array of polymer spheres or a regular array of polymeric blocks in a phase-separating polymer film.

8121687, Feb 21, 2012

Oct 31, 2005

11/718201

Marc Jensen - Los Gatos CA, US
Todd Thompson - San Jose CA, US
Olivier Colliou - Los Gatos CA, US
George M. Savage - Portola Valley CA, US
Mark J. Zdeblick - Portola Valley CA, US
Jeremy Frank - San Francisco CA, US
Lawrence W. Arne - Redwood City CA, US
Robert White - Stanford CA, US

Proteus Biomedical, Inc. - Redwood City CA

A61N 1/18

607 17, 607 6, 607 18, 607 19, 607 22

Methods for evaluating motion of a cardiac tissue location, e. g. , heart wall, are provided. In the subject methods, timing of a signal obtain from a strain gauge stably associated with the tissue location of interest is employed to evaluate movement of the cardiac tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.

2012007, Mar 29, 2012

May 19, 2010

13/319974

Mark Zdeblick - Portola Valley CA, US
Robert White - Stanford CA, US

A61N 1/372, A61B 5/053

600547, 607 62

A method and device are provided that detect and identify a neural signal by type and optionally or automatically provide a signal that affects a nerve carrying the neural signal. A plurality of electrodes is positioned along a nerve and monitors the electrical activity of the nerve. The invented system analyzes the monitored data to determine when the monitored activity can be identified as a known type of bioelectric signal, e.g., a pain nerve signal. The system may optionally attempt to affect, disrupt, diminish, nullify or block transmission of bioelectric signals along the nerve, e.g., by directing electrical energy through an electrode to nullify a bioelectric signal along a pain nerve.

7615382, Nov 10, 2009

Nov 9, 2006

11/595818

Shan X. Wang - Portola Valley CA, US
Nader Pourmand - San Mateo CA, US
Robert L. White - Stanford CA, US

The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA

G01N 33/553, B03C 1/30

436526, 436518, 436538, 209 38, 209214, 209215

The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The magnetic sifter includes at least one substrate. Each substrate contains a plurality of slits, each of which extends through the substrate. The sifter also includes a plurality of magnets attached to the bottom surface of the substrate. These magnets are located proximal to the openings of the slits. An electromagnetic source controls the magnitude and direction of magnetic field gradient generated by the magnets. Either one device may be used, or multiple devices may be used in series. In addition, the magnetic sifter may be used in connection with a detection chamber.