Inventors:
Jonathan Stamler - Boston MA
Joseph Loscalzo - Dedham MA
Adam Slivka - Randolph MA
Daniel Simon - Waban MA
Robert Brown - Natick MA
Jeffrey Drazen - Winchester MA
Assignee:
Brigham & Women's Hospital - Boston MA
International Classification:
A61K 31195, A61K 3113
Abstract:
Methods of relaxing corpus cavernosum smooth muscle, treating disease states responsive to prevention or relaxation of undesirable contractions of corpus cavernosum smooth muscle and of treating male impotence by administering an S-nitrosothiol such as a low molecular weight S-nitrosothiol, S-nitroso-ACE-inhibitor or S-nitroso-protein.